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Tofacitinib is effective and safe for severe hair loss, but full regrowth is less likely after 10 years of hair loss.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.

Nerves are crucial for the regeneration of various body parts in many animals.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

A patient with Alopecia Areata had complete hair regrowth after using the drug baricitinib.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

Some treatments can help with a hair loss condition called alopecia areata, but none ensure lasting results; choices depend on the person, with JAK inhibitors showing promise for severe cases.

Special fiber materials boost the healing properties of certain stem cells.

Fibrinogen/LDL apheresis may improve speech perception in sudden hearing loss, especially for those with high fibrinogen and LDL levels.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Myrtle has various health benefits and potential for medicine development.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.