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Scientists created a functional 3D skin system from stem cells that can be transplanted into wounds.

Removing Dicer from pigment cells in newborn mice causes early hair graying and changes in cell migration molecules.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

Patients with Systemic Sclerosis have much higher levels of GDF-15, which could help predict organ involvement and guide treatment.

CCCA is a scarring hair disorder mainly affecting people of African descent, needing better awareness and treatment.

Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.

Tiger cubs fed artificial milk lacking certain amino acids developed eye problems and hair loss.

The document concludes that an experimental drug may help wound healing in Epidermolysis Bullosa, links Hydroa vacciniforme to EBV, discusses diagnosing hair loss disorders, finds many children with eczema have allergies, reviews the safety of a skin medication in children, notes side effects of a Duchenne's treatment, and identifies a marker for pediatric mastocytosis.

Skin problems are common in lupus, often appearing first, with various types and treatments, and careful monitoring is important for diagnosis and management.

New skin disease treatments using TDDS are improving but face challenges like side effects and high costs.

FDA-cleared devices may help treat hair loss, but more research needed; consult dermatologist before use.

Certain medications and patient factors increase the risk of Intraoperative Floppy Iris Syndrome during cataract surgery, but with careful planning and technique adjustments, complications can be minimized.

Melatonin, the sleep hormone, can help treat skin conditions like dermatitis, hyperpigmentation, and scalp disorders, and may also aid in skin aging prevention and regeneration. However, it's not recommended for asthma due to its pro-inflammatory effect.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

Metabolic syndrome's individual issues are real and need treatment to reduce diabetes and heart disease risks.

The document concludes that drug repurposing, which is reusing known medicines for new illnesses, can provide faster, cheaper treatment options for various serious diseases, including cancer, COVID-19, and rare diseases.

Minoxidil nanoparticles significantly boost hair growth in mice compared to regular minoxidil.

The conclusion is that fat grafting is safe and effective but carries risks that need careful management.

Some skin diseases and their treatments can negatively affect male fertility.

Caffeine shows promise for treating some types of hair loss, but more research is needed.

Eyelash alopecia areata often goes undiagnosed and can lead to complete eyelash regrowth, especially in younger patients.

Some cosmetics and dermatological drugs can cause allergic reactions and side effects, like skin irritation and systemic issues.

The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.

Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.

Use antimalarials like hydroxychloroquine for cutaneous lupus, avoid herbal supplements, and focus on lifestyle changes like sun protection.

Ellis van Creveld syndrome, a rare genetic disorder, can cause unexpected abnormalities in various body organs, requiring thorough patient evaluations.

Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.

β-blockers can cause skin problems like psoriasis and vitiligo, and doctors should tell patients about these risks.