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The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Genetic variations affect dutasteride treatment response for male pattern hair loss.

People with alopecia areata have higher levels of RBP4 protein and antibodies against it.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

DGAT1 enzyme is crucial for healthy skin and hair by regulating retinoid levels.

Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.

Excess androgens may cause PCOS, not just be a symptom.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

CD201+ fascia progenitors are essential for wound healing and could be targeted for treating skin conditions.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Retinoic acid affects male and female muscle energy use and function differently.

Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.

Vitamin A is important for healthy skin and hair, influencing hair growth and skin healing, but UV light reduces its levels.

Eating too much or too little vitamin A can cause hair loss.

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

Estrogen affects how vitamin A is processed in mouse skin, which may impact acne treatment, hair growth, and skin defense.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Sdr16c5 and Sdr16c6 genes regulate a key point in lipid production that affects eye and skin gland function.