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Melatonin, the sleep hormone, can help treat skin conditions like dermatitis, hyperpigmentation, and scalp disorders, and may also aid in skin aging prevention and regeneration. However, it's not recommended for asthma due to its pro-inflammatory effect.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.

Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.

Vitamin D boosts a specific gene activity in kidney cells that could improve heart and kidney function.

Botanical extracts are increasingly important in cosmetics and drugs for their effectiveness and safety, backed by traditional use and scientific evidence.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Low-potency steroids can cause serious side effects in people with skin conditions like Netherton syndrome.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Active transdermal technologies in cosmetics help deliver skin treatments effectively, but their safety and effectiveness depend on skin type and treatment choice.

Some chemicals absorbed through the skin can cause serious health problems.

Microneedling combined with skinbooster effectively treats striae rubrae, with confocal microscopy confirming collagen changes.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

The document concludes that dermatology training and grading scales need to better represent dark-skinned individuals to improve diagnosis and assessment of skin conditions.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Hormonal therapies are safe and effective for treating adult women's acne.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Mutations in certain receptors can cause diseases and offer new treatment options.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

CD201+ fascia progenitors are essential for wound healing and could be targeted for treating skin conditions.

Many adult women suffer from persistent or late-onset acne, and while various treatments exist, finding the right one can be challenging.

The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.

The document concludes that proper treatment and management of plaque psoriasis in adolescents can improve their quality of life.

Acne in children varies by age and severity, requires a pediatric treatment approach, and may need diagnostic evaluation for underlying conditions.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.