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    Glossary Retinoids

    compounds derived from vitamin A used in skincare and medicine

    Retinoids are a class of compounds derived from vitamin A that are commonly used in skincare and medical treatments. They play a crucial role in regulating cell growth, differentiation, and apoptosis, making them effective for treating conditions like acne, psoriasis, and certain types of alopecia. Retinoids can also help reduce wrinkles and improve skin texture by promoting collagen production.

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    1. Differential expression of retinoic acid-synthesizing (RALDH) enzymes during fetal development and organ differentiation in the mouse Mechanisms of development · 2002 · 232 citations
    2. Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled EMBO journal · 2002 · 127 citations
    3. Oral retinoids-present status British Journal of Dermatology · 1980 · 108 citations
    4. Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression (Catagen) by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla Journal of Investigative Dermatology · 2005 · 92 citations
    5. Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin 2008 · 91 citations
    6. Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplastic skin reveals roles for β-catenin and Notch signalling Developmental biology · 2008 · 84 citations
    7. Topical Retinoids: Therapeutic Mechanisms in the Treatment of Photodamaged Skin American journal of clinical dermatology · 2016 · 69 citations
    8. Self-assembled polymeric nanocarriers for the targeted delivery of retinoic acid to the hair follicle Nanoscale · 2015 · 59 citations
    9. Endogenous Retinoids in the Pathogenesis of Alopecia Areata 2012 · 54 citations
    10. Oral Retinoids in Dermatology International Journal of Dermatology · 1981 · 52 citations
    11. Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk Nature Communications · 2014 · 51 citations
    12. Endogenous retinoids in the hair follicle and sebaceous gland Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2011 · 50 citations
    13. The role of retinoids in the management of cutaneous conditions in blacks Journal of the American Academy of Dermatology · 1998 · 48 citations
    14. The use of a retinoid receptor antagonist in a new model to study vitamin A-dependent developmental events. PubMed · 1998 · 44 citations
    15. In situ detection of retinoid-X receptor expression in normal and psoriatic human skin 1995 · 42 citations
    16. Two Opposing Faces of Retinoic Acid: Induction of Stemness or Induction of Differentiation Depending on Cell-Type Biomolecules · 2019 · 41 citations
    17. Treatment of Psoriasis vulgaris with a New Retinoic Acid Derivative Ro 10-9359 Dermatology · 1977 · 39 citations
    18. Regulation of human dermal papilla cell production of insulin-like growth factor binding protein-3 by retinoic acid, glucocorticoids, and insulin-like growth factor-1 Journal of cellular physiology · 1996 · 37 citations
    19. Polymer conjugated retinoids for controlled transdermal delivery Journal of controlled release · 2017 · 36 citations
    20. Expression of retinoid nuclear receptor superfamily members in human hair follicles and its implication in hair growth. Acta Dermato Venereologica · 1997 · 34 citations
    21. Retinoids and Keratinization International Journal of Dermatology · 1988 · 32 citations
    22. The Aldo-Keto Reductase AKR1B10 Is Up-Regulated in Keloid Epidermis, Implicating Retinoic Acid Pathway Dysregulation in the Pathogenesis of Keloid Disease Journal of Investigative Dermatology · 2016 · 31 citations
    23. Cutaneous Retinoic Acid Levels Determine Hair Follicle Development and Downgrowth 2012 · 31 citations
    24. Chemotherapy of psoriasis and other skin disorders with oral retinoids Pharmacology & Therapeutics · 1981 · 31 citations
    25. Hairless Modulates Ligand-Dependent Activation of the Vitamin D Receptor-Retinoid X Receptor Heterodimer Biological & pharmaceutical bulletin · 2012 · 28 citations
    26. Monilethrix treated with oral retinoids Clinical and experimental dermatology · 1991 · 26 citations
    27. Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways Journal of Cellular Biochemistry · 2005 · 24 citations
    28. Cellular localization of retinoic acid receptor-gamma expression in normal and neoplastic skin. PubMed · 1992 · 23 citations
    29. Retinoid Metabolism Is Altered in Human and Mouse Cicatricial Alopecia Journal of Investigative Dermatology · 2012 · 22 citations
    30. Antipsoriatic Activity of a New Synthetic Retinoid Archives of dermatology · 1983 · 20 citations