69 citations
,
March 2016 in “American journal of clinical dermatology” Topical retinoids effectively improve photodamaged skin.
1 citations
,
September 2022 in “TURKDERM” This study found that using isotretinoin and acitretin was not linked to a higher risk or severity of COVID-19 in patients undergoing systemic retinoid therapy.
June 2023 in “University of Thi-Qar Journal of Science” This review discusses the various uses of retinoids, derived from vitamin A, in cosmetic and dermatological treatments for conditions like acne, psoriasis, and skin aging. The authors emphasize retinoids' limited use due to their susceptibility to degradation and safety concerns, particularly with retinoic acid.
May 2025 in “Journal of Nanobiotechnology” This study reported that an ATRA-loaded nanostructured lipid carrier gel (ATRA-NLC-Gel) improved symptoms of alopecia areata in mice by enhancing transdermal drug delivery, reducing skin irritation, and promoting hair regrowth through targeted follicle enrichment and pathway activation.
4 citations
,
March 2022 in “Cosmetics” This review suggests that a dual treatment approach using Nourella® cream with nano-encapsulated Retilex-A® and per-oral Vercilex® tablets may effectively improve skin thickness, elasticity, and overall rejuvenation in aging skin, as shown in interventional studies.
October 2025 in “Annals of Medicine and Surgery” This study discusses the potential of topical retinoids, vitamin A derivatives, to improve treatment outcomes for androgenetic alopecia by promoting hair growth through extending the anagen phase and stimulating follicular activity, offering a promising approach when combined with existing therapies.
September 2025 in “Frontiers in Cell and Developmental Biology” In this review, retinoids are highlighted as promising agents for promoting scarless skin regeneration by coordinating cellular and molecular processes that suppress fibrosis, enhance re-epithelialization, promote angiogenesis, and enable hair follicle formation, potentially advancing functional skin repair.
March 2024 in “Ukraïnsʹkij žurnal dermatologìï, venerologìï, kosmetologìï” This source highlights that topical retinoids, particularly adapalene and its combinations, are crucial in treating acne due to their rapid action, sustained effects, and good tolerability; the study underscores the enhanced patient adherence with Deriva C MS gel for acne treatment.
January 2026 in “Annals of Medicine and Surgery” This article corrects an author name in a previously published study on the application of retinoids for androgenic alopecia, without presenting new research findings.
108 citations
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November 1980 in “British Journal of Dermatology” This article reviews the current status of oral retinoids in dermatology and reports no new clinical findings.
10 citations
,
March 1990 in “The Journal of Dermatology” In this study, a psoriatic patient developed retinoid-induced granulation tissue after long-term oral etretinate therapy, suggesting prolonged use may lead to delayed wound healing.
4 citations
,
September 2014 in “Elsevier eBooks” This review discusses the safety of dermatological medications used during pregnancy, highlighting that retinoids have strong teratogenic risks and should be used with caution; it reports no new clinical results.
42 citations
,
August 2016 in “Nanomedicine” In this study, TyroSpheres were used to encapsulate adapalene, increasing its solubility and enhancing skin distribution while reducing irritancy compared to a commercial formulation, indicating promise for acne treatment in ex vivo and in vitro settings.
37 citations
,
April 2019 in “Journal of The American Academy of Dermatology” This review assessed the effectiveness of various treatments for frontal fibrosing alopecia and found that intralesional steroids and 5α-reductase inhibitors showed the most positive outcomes in slowing or halting hair loss, though the lack of placebo-controlled studies and consistent outcome measures limits definitive conclusions.
20 citations
,
January 2000 in “Dermatologic Clinics” This article discusses recent advancements in treatments for psoriasis, including new drug approvals and innovative therapeutic approaches, but reports no new clinical results.
4 citations
,
December 2021 in “Experimental and Therapeutic Medicine” This article describes adult female acne as a complex condition affected by genetic, hormonal, and environmental factors, with hormonal therapies highlighted as particularly valuable for treatment.
1 citations
,
June 2014 in “Journal of developmental biology” This study found that retinoic acid induces epidermal transdifferentiation into mucosal epithelium in both chick and mammalian embryonic skin, involving specific gene expressions and pathways.
15 citations
,
January 2014 in “Anais Brasileiros de Dermatologia” This review discusses the varied cutaneous manifestations of Systemic Lupus Erythematosus and outlines treatment approaches, but it reports no new clinical findings.
11 citations
,
October 1990 in “The Journal of dermatologic surgery and oncology” This review discusses the potential for new retinoids, topical antiandrogens, and alternative therapies to surpass tretinoin in treating cutaneous aging, but reports no clinical results.
9 citations
,
December 2015 in “Journal of Dermatological Case Reports” A 12-year-old with ichthyosis linearis circumflexa showed significant improvement after 30 sessions of narrowband UVB phototherapy, as reported in this case study.
7 citations
,
May 2010 in “Drug Delivery” This study found that retinoic acid pre-treatment enhanced the efficiency of gene transfer into mouse skin for potential therapeutic applications.
September 1986 in “Journal of the American Academy of Dermatology” This conference summary covers advancements in dermatology, including aging skin and acne therapies, but reports no new experimental results.
January 1988 in “Inpharma (Balgowlah)” New retinoids are effective for various skin conditions and are being developed to have fewer side effects.
5 citations
,
February 2013 in “Expert Review of Dermatology” New acne treatments include combination creams, advanced retinoids, and light therapies, focusing on safety and patient adherence.
5 citations
,
May 2017 in “Current Opinion in Pediatrics” This review found that hormonal therapies, including FDA-approved combined oral contraceptive pills and spironolactone, are effective and well-tolerated treatments for acne vulgaris in adolescents with or without endocrine disorders, providing alternative options to antibiotics.
1 citations
,
October 2022 in “Adolescent Health, Medicine and Therapeutics” This article discusses the dermatologic impacts of gender-affirming medical care in transgender adolescents and emphasizes the importance of patient-centered care to improve dermatologic and overall outcomes; it reports no new clinical results.
January 2005 in “Farmaceutski glasnik” This review discusses various substances used in the treatment of alopecia, highlighting the roles of minoxidil and finasteride, but reports no new experimental findings.
5 citations
,
August 2015 in “British journal of dermatology/British journal of dermatology, Supplement” The top research priorities for congenital ichthyosis include long-term side effects of oral retinoids, best topical treatments, and treatments for itch and hair loss.
38 citations
,
August 1999 in “New England journal of medicine/The New England journal of medicine” This letter discusses observations of indinavir's effects on skin, likening them to those of retinoids, but does not present new clinical findings.
4 citations
,
July 1996 in “Annals of Internal Medicine” This article discusses a report on reversible alopecia associated with fluconazole therapy and mentions other possible causes of hair loss but presents no new findings.