1 citations
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January 2018 in “Indian Journal of Dermatology/Indian journal of dermatology” This report describes cases of transient thyrotoxicosis potentially linked to oral retinoid treatment, suggesting a possible mechanism involving increased iodine uptake by thyroid cells.
January 2023 in “Side effects of drugs annual” This chapter reviews emerging side effects of various nutritional supplements and alternative medicine practices, highlighting potential toxicities and stressing the need for careful identification and management by healthcare professionals.
38 citations
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November 2012 in “Expert Opinion on Drug Safety” This article reviews different acne treatments and emphasizes the importance of being aware of their potential side effects, but reports no new clinical results.
This review highlights concerns about dermatological side effects linked to rapid weight loss from glucagon-like peptide-1 receptor agonists used for type 2 diabetes and obesity treatment, such as skin laxity, decreased collagen, and hair loss, emphasizing the importance of managing these while retaining metabolic benefits.
This article reviews different generations of synthetic retinoids for dermatological use, discussing their efficacy and significant side effects, but reports no new clinical results.
July 2025 in “Annals of Human Genetics” This review examines the genetics of acne vulgaris, concluding that stem/progenitor cell maintenance and cellular migration are key processes in its pathogenesis, potentially shifting future treatment strategies beyond traditional antibiotics and retinoids, which have notable side effects.
3 citations
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October 2019 in “CRC Press eBooks” This review discusses isotretinoin's effectiveness against severe acne vulgaris and its associated side effects, including teratogenicity and hair loss, but it reports no new experimental results.
25 citations
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May 2018 in “Clinical & Translational Oncology” This review summarizes common skin-related side effects of BRAF inhibitors and immunotherapy in advanced melanoma treatment, reporting no new clinical findings, and emphasizes consensus management to improve patient outcomes.
53 citations
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October 1993 in “Drug Safety” Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.
April 1982 in “Journal of The American Academy of Dermatology” Retinoids help treat psoriasis effectively, but they can cause side effects and need more research on safe use with other treatments.
January 2026 in “International Journal of Innovative Technologies in Social Science” This review synthesizes information on isotretinoin’s systemic toxicity, emphasizing that its adverse effects, including mucocutaneous, hepatic, and musculoskeletal reactions, primarily reflect its pharmacodynamic actions and are generally manageable with individualized dosing and monitoring, though its teratogenicity remains a significant safety concern.
September 1988 in “Inpharma (Balgowlah)” Retinoids are effective for acne but can cause serious side effects.
12 citations
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January 2011 in “Dermatologic Surgery” This entry contains only a placeholder abstract with no research findings described or summarized.
75 citations
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August 2005 in “Expert Opinion on Pharmacotherapy” This review discusses the use of acitretin, a retinoid approved since 1997, for various forms of psoriasis and its potential benefits in combination therapy, but reports no new clinical findings.
39 citations
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January 1977 in “Dermatology” This study found that the retinoic acid derivative Ro 10-9359 cleared psoriasis lesions in over half of the patients, but most experienced side effects, including skin issues and altered liver enzyme levels.
24 citations
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July 1983 in “Clinical and Experimental Dermatology” Tigason improved hair growth in a boy with monilethrix without side effects.
52 citations
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June 1981 in “International Journal of Dermatology” Oral retinoids are effective for severe skin conditions but require careful use due to side effects.
This article discusses the roles of retinoic acid in cellular differentiation and its side effects like hair loss, but reports no new clinical findings.
January 1988 in “Inpharma (Balgowlah)” New retinoids are effective for various skin conditions and are being developed to have fewer side effects.
January 1990 in “Irish Journal of Medical Science (1971 -)” Retinoids are important for treating skin conditions but should be used with caution due to serious side effects and risks during pregnancy.
6 citations
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December 1987 in “Mayo Clinic proceedings” This article reviews the use of retinoids, such as tretinoin, isotretinoin, and etretinate, in dermatological treatments, highlighting their efficacy and side effects, but presents no new clinical findings.
January 2017 in “Clinical approaches and procedures in cosmetic dermatology” This research outlines how retinoids, compounds based on vitamin A, activate nuclear receptors to influence cellular processes such as differentiation and carcinogenesis, with benefits like anti-inflammatory properties but requiring careful management of dose-dependent side effects.
20 citations
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September 1983 in “Archives of dermatology” This study observed that minimal doses of the arotinoid RO 13-6298 successfully treated two cases of severe psoriasis and psoriatic arthritis unresponsive to traditional therapies, despite some side effects.
12 citations
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October 1978 in “PubMed” This study found that the aromatic retinoic acid derivative Ro 10-9359 provided excellent results in 64% of severe psoriasis patients, especially in those with erythrodermic and pustular types, though relapses and side effects were noted.
1 citations
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June 2016 in “Annals of the rheumatic diseases” In this study, researchers found that retinoids might improve lupus nephritis resistant to conventional treatments, but the sample size was too small for significant results, and side effects were noted.
52 citations
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February 2003 in “Archives of dermatology” In this open-label trial, 9-cis-retinoic acid showed moderate activity against Kaposi sarcoma in AIDS patients, but its use is limited by substantial side effects at higher doses.
August 1994 in “Drugs & Therapy Perspectives” Psoriasis treatments range from topical creams to systemic medications with serious side effects, and while treatments can manage symptoms, there is no cure.
31 citations
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February 1982 in “Archives of dermatology” This study found that oral etretinate improved skin conditions like erythrodermic and pustular psoriasis, although less so for psoriasis vulgaris and lichen planus, with notable side effects including cheilitis and mucous membrane dryness.
5 citations
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August 2015 in “British journal of dermatology/British journal of dermatology, Supplement” The top research priorities for congenital ichthyosis include long-term side effects of oral retinoids, best topical treatments, and treatments for itch and hair loss.
April 2022 in “JAAD case reports” In this case report, researchers found that alitretinoin was an effective treatment for a case of generalized granuloma annulare that was previously unresponsive to multiple other therapies.