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Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.

Human skin xenografting could improve our understanding of skin development, renewal, and healing.

Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.

The ABCA4 gene protects hair follicle stem cells from toxic vitamin A byproducts.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

9-cis-retinoic acid showed some effectiveness in treating AIDS-related Kaposi sarcoma but had significant side effects at higher doses.

The vitamin D receptor can work without its usual activating molecule.

Thyroid hormone receptors are essential for hair growth and wound healing.

High-dose vitamin A and E with zinc improved blood sugar control and insulin function in diabetics, but may cause hair loss.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Collagen and TGF-β2 help maintain hair cell shape and youthfulness.

Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

Retinoic acid affects male and female muscle energy use and function differently.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.

Different types of skin fibroblasts have unique roles in skin health and disease.

RORA may help regulate hair growth by affecting hair follicle stem cells.

Extracorporeal shock waves significantly improve hair growth in women with female pattern hair loss.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.

PROTO1 and PROTO2 protect against hearing damage.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

Vemurafenib causes skin side effects similar to RASopathies, requiring regular skin checks and UVA protection.

Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.

Topical calcitriol-analogs can reduce hair loss caused by chemotherapy.