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Hairless protein can block vitamin D activation in skin cells.

Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.

Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.

T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.

A girl with a rare skin condition called Keratosis Follicularis Spinulosa Decalvans showed no significant improvement with treatment.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.

Fzd2 is important for skin and hair development through various signaling ways.

Older hair follicle stem cells have a reduced ability to renew themselves, leading to more hair loss.

Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.

Activating Nrf2 helps wounds heal faster by increasing hair follicle stem cells.

Topical tofacitinib is effective in promoting hair growth for non-scarring alopecia.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

Increased PPARGC1α relates to hair thinning in common baldness.

A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.

TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.

The RORα gene is active in different parts of cashmere goat hair follicles and may be influenced by melatonin, especially in December when hair growth changes.

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.

Two different mutations in the vitamin D receptor gene cause different symptoms and responses to treatment in Lebanese patients with hereditary rickets.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.