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Nanomaterials show promise in improving wound healing but require more research on their potential toxicity.

Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

Disrupting β-catenin signaling in certain cells causes anorectal malformations.

Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.

Adipokines affect skin health and could be targeted for treating skin diseases.

Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.

TGase 3 helps build hair structure by forming strong bonds between proteins.

VDR regulation varies by tissue and is crucial for its biological functions.

iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Minoxidil and finasteride are the best for non-scarring hair loss; more research is needed for scarring hair loss treatments.

Activating Notch signaling can kill basal cell carcinoma cells.

Human hair follicles can be used to create stem cells that might help clone hair for treating hair loss or helping burn patients.

Activating Nrf2 can help protect against hearing loss.

Erosive pustular dermatosis in elderly people may be linked to aging immune systems and skin damage.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Intermediate filaments are crucial for cell differentiation and stem cell function.

Excessive sun protection might cause frontal fibrosing alopecia by disrupting skin immune balance.

Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Experts advise using sunscreen and proper skin care before, during, and after procedures to speed healing, prevent complications, and reduce scarring.

Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.

Zinc is important for skin health, and supplements can help treat various skin and hair disorders, but more research is needed for conditions like psoriasis and vitiligo.

Zinc is crucial for skin health and treating various skin disorders.

White blood cells and their traps can slow down the process of new hair growth after a wound.