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Genetics play a role in acne, but how exactly they contribute is not fully understood.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Adrenal disorders can cause lasting brain and behavior issues in children.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Type I interferons play a key role in the development of various skin diseases.

Pannexin 3 is important for bone formation and the development of bone cells.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.

Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.

Lower CD200R1 on certain immune cells is linked to more severe rheumatoid arthritis and immune imbalance.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.

The conclusion is that better understanding and more research are needed to effectively manage follicular and scarring disorders in skin of color, with an emphasis on patient education and cultural awareness.

Alopecia areata is an autoimmune hair loss condition treated with corticosteroids, and histologic confirmation is the best diagnosis method.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

Thyroid hormone may speed up wound healing and hair growth, but more research is needed to understand its role in skin repair and use as a treatment.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Early recognition and management of skin side effects from new cancer therapies can prevent treatment delays.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Researchers created a skin treatment that could effectively deliver medication into hair follicles.

Topical vitamin D is useful for some skin conditions but not effective for others, and more research is needed.

The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.

Skin lymphatic vessels are essential for hair growth.