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New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Notch-related genes play a key role in the development and cycling of hair follicles.

Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.

A 14-year-old girl with no menstrual period was diagnosed with Swyer Syndrome and treated for a related cancer risk.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Nutrients like vitamins, copper, zinc, and amino acids are crucial for healthy hair and wool growth.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Pannexin 3 is important for bone formation and the development of bone cells.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.

Goat skin changes with the seasons due to genes affected by daylight and hormones.

The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.

The vitamin D receptor can work without its usual activating molecule.

Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.