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Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.

Disrupting natural body clocks increases the risk of developing type 2 diabetes.

Melatonin applied to the scalp helps increase hair density in people with early hair loss.

Melatonin applied to the scalp helps treat early-stage hair loss in men and women.

BMAL1 controls skin cell growth and UV damage risk, peaking at night.

Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.

Hairless protein affects hair follicle structure by regulating the Dlx3 gene.

Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.

Melatonin, the sleep hormone, can help treat skin conditions like dermatitis, hyperpigmentation, and scalp disorders, and may also aid in skin aging prevention and regeneration. However, it's not recommended for asthma due to its pro-inflammatory effect.

Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

Melatonin could be an effective treatment for Alzheimer's Disease and rosacea.

B6.Cg-Tyr c−2J Hr hr /J mice have a stronger delayed sunburn reaction and are good for UV research.

Natural skincare products may help reduce sun damage and support the skin's daily cycle.

Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.

All-trans-retinoic acid stops mink hair growth by affecting cell growth and causing cell death.

BMPR1a-ECD reduces wrinkles much more effectively than retinoic acid.

Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.

Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.

Retinoic acid, glucocorticoids, and IGF1 increase IGFBP-3 production in human dermal papilla cells, affecting hair growth.

The document discusses various skin disorders and new therapeutic approaches.

Hair casts are often mistaken for head lice, scalp pain in hair loss is linked to certain nerve factors, eyelash growth treatment is safe and effective, and nail shedding in children may follow hand-foot-mouth disease.

Mutations in the P2RY5 gene cause hereditary woolly hair.

Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.

Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Hair follicle stem cells prevent melanocyte stem cells from differentiating by controlling retinoic acid levels.

Eating vitamin A affects hair growth and health by changing cell signals in mice.