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The skin and thymus develop similarly to protect and support immunity.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

miR-195-5p reduces hair growth ability in cells by blocking a specific growth signal.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.

Chemotherapy in children often causes hair loss, nausea, vomiting, and mood swings.

Certain gene mutations can weaken the skin barrier and, when combined with environmental factors, lead to eczema and severe itching.

Polyomavirus A2 infection in newborn mice caused hair follicle tumors.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Cancer development is like natural selection, involving mutated cells and environmental factors.

Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Green-synthesized nanoparticles can effectively target cancer cells, reducing side effects and improving treatment.

Genomic approach finds new possible treatments for hair loss.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.

Costunolide helps human hair cells grow and can stimulate hair growth in mice.

Vitamin D receptor may help protect against UV-induced skin cancer.

The substance DMC helps get rid of aging cells by triggering a process that causes cell death, which could treat age-related diseases.

Deleting the MAD2L1 gene is tolerated in certain mouse cancer models.

Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.