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Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Sulforaphane from broccoli can help protect skin from sun damage.

Myrtle has various health benefits and potential for medicine development.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Eating disorders like anorexia and bulimia cause skin problems, and dermatologists can help detect these disorders early for better treatment outcomes.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.

Voriconazole can cause serious side effects, especially in long-term use.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.