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Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Stem cell self-renewal is complex and needs more research for full understanding.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Cathepsin L is essential for normal hair growth and development.

Too much androgen can cause hair loss; finasteride may help.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

Understanding hair follicle anatomy helps diagnose hair disorders.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Finasteride effectively blocks enzyme causing male pattern baldness.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Tofacitinib may help treat severe hair loss, but more research is needed.

PEVs improve minoxidil skin penetration, increasing hair growth.

Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Fat cells in the skin help start healing and form important repair cells after injury.