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This study found that the vitamin D receptor in lampreys, which lack bones and hair, binds 1,25-dihydroxyvitamin D3 and may function to induce enzymes for detoxifying substances.

This study found that laminin-511 is crucial for hair morphogenesis in mice, as it influences primary cilia formation and dermal papilla maintenance through noggin and sonic hedgehog signaling.

This review noted that alopecia areata is an autoimmune disease impacting hair follicles and offered insights into its complex pathogenesis involving immune responses, while highlighting ongoing research into new treatments such as Janus kinase inhibitors and other immunomodulatory drugs.

This review discusses evidence-based guidance for managing primary cicatricial alopecias but reports no new clinical results, highlighting significant gaps in knowledge and the need for more quality trials.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

This review summarizes recent multidisciplinary advances in sebaceous gland research and highlights potential novel therapeutic strategies for skin diseases, but it reports no new clinical results.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

This narrative review discusses lichen planus pigmentosus, including its variations, associated triggers, and management strategies, but reports no new clinical results.

This study found that patients with acne vulgaris had higher serum IGF-1 levels and more intense FoxO1 and mTOR expression than controls, suggesting their role in acne pathogenesis.

This study found that newborn mouse skin organoids can robustly grow hair in vivo, while adult organoids require specific interventions to restore their hair-forming ability.

This study suggests that spironolactone-loaded nanostructured lipid carriers could enhance follicular delivery and offer a more localized treatment for androgenic alopecia, potentially reducing systemic side effects.

In this study, 19 patients treated with finasteride for androgenetic alopecia developed moderate to severe depression, which resolved after stopping the medication, suggesting an association between finasteride and mood disturbances.

This review examines the evolving field of nanozymes, highlighting their unique properties and biocatalytic capabilities that challenge traditional concepts of biocatalysis, with implications for sustainable applications and potential roles in physiological processes and disease pathogenesis.

Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.

This retrospective study found that adipose-derived stem cell-conditioned media increased hair density and thickness in women with female pattern hair loss over 12 weeks, with no severe adverse effects reported.

This review explores animal models of alopecia areata, particularly focusing on the insights they've provided into the disease's immune mechanisms and potential treatment approaches, without reporting new experimental data.

This study found that silencing clock genes BMAL1 or PER1 in human hair follicles increased melanin content and melanocyte activity, suggesting these genes influence pigmentation.

This study found that scalp sensitivity frequently occurs in the French population and is associated with various symptoms and triggers, differing from facial skin sensitivity.

This review discusses recent advances and ongoing clinical trials in novel therapeutics for alopecia areata, despite the lack of current FDA-approved treatments for severe cases, and reports no new results.

This review discusses the diagnosis, treatment, and management of atopic dermatitis in developing countries and identifies significant unmet medical needs, particularly in access to care and effective treatments; it reports no clinical results.

This article reviews common hair-care practices among African American patients and discusses how these practices relate to hair and scalp disorders, without presenting new clinical research.

This review discusses follicular transplantation for hair restoration, highlighting the importance of evaluating patient suitability and careful planning to achieve excellent cosmetic outcomes, but reports no new research findings.

This article discusses the complexities of diagnosing and managing polycystic ovary syndrome in adolescents and highlights the lack of established diagnostic criteria and unclear clinical implications, without presenting new clinical findings.

This study found that oral finasteride was more effective than 5% topical minoxidil in treating mild to severe androgenetic alopecia in males, with both treatments deemed effective and safe over 12 months.

This study found that short-chain fatty acids produced by the skin microbe Propionibacterium acnes may drive inflammatory gene expression in sebocytes, potentially contributing to acne.

This study found that systematic review and protocol topics in the Cochrane Database for skin conditions are partly aligned with disease burden metrics, with some conditions overrepresented and others underrepresented compared to their disability-adjusted life years.

This review found that lifestyle changes, such as diet and exercise, are beneficial for managing metabolic and endocrine abnormalities in obese patients with PCOS and suggests combining these with anti-obesity agents for enhanced effects.

This study found that securinine and ajmaline significantly inhibited hepatocellular carcinoma cell viability and induced apoptosis, with securinine showing lower toxicity to normal liver cells.

This review examines the role of nuclear hormone receptors in skin wound repair processes and reports no new clinical results, highlighting the importance of their interaction with skin cells for effective healing.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.