180 citations
,
July 1973 in “The New England Journal of Medicine” In this study, minoxidil effectively reduced blood pressure to near normal levels in patients with malignant or accelerated hypertension resistant to conventional treatments, offering a potential alternative to nephrectomy.
108 citations
,
October 2004 in “Anesthesiology” This review discusses surgical factors that may increase the risk of developing complex regional pain syndrome and describes potential preventive techniques but presents no new clinical results.
100 citations
,
March 1973 in “American Journal of Cardiology” Minoxidil effectively lowers blood pressure without major side effects.
74 citations
,
March 1963 in “Archives of Dermatology” This article reviews historical reports of skin changes, such as pseudoacanthosis nigricans, associated with cholesterol-lowering drugs like triparanol and nicotinic acid, but presents no new clinical findings.
60 citations
,
June 2017 in “IOSR Journal of Pharmacy (IOSRPHR)” This review highlights the chemical components and various potential health effects of Daucus carota but reports no new experimental results.
57 citations
,
January 1980 in “Journal of Cardiovascular Pharmacology” Minoxidil treats high blood pressure and side effects can be managed.
55 citations
,
October 1975 in “Circulation” Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.
52 citations
,
March 1979 in “Toxicology and Applied Pharmacology” Minoxidil can cause heart muscle damage in dogs.
50 citations
,
September 1975 in “American Heart Journal” Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.
45 citations
,
February 2018 in “Journal of basic and clinical physiology and pharmacology/Journal of basic & clinical physiology & pharmacology” This review summarizes the ethno-medicinal uses, phytochemical constituents, and biological activities of Acorus calamus, highlighting its potential therapeutic benefits and the importance of further scientific work on this plant.
43 citations
,
May 1978 in “JAMA” Minoxidil controls blood pressure but may cause kidney damage and needs diuretics to prevent swelling.
41 citations
,
April 2010 in “Gender Medicine” This review discusses the causes, clinical features, diagnostic approach, and treatment options for hirsutism in women, but reports no new findings.
36 citations
,
February 2017 in “BMC Complementary and Alternative Medicine” In this study, Geranium sibiricum L. extract promoted hair growth in vitro with human dermal papilla cells and in vivo in mice, outperforming minoxidil by proliferating cells and stimulating growth factor expression, suggesting its potential as a hair growth treatment.
36 citations
,
July 1977 in “The Journal of Pediatrics” Minoxidil helps lower blood pressure in kids with severe hypertension, but may cause temporary excessive hair growth.
35 citations
,
December 1979 in “Naunyn-schmiedebergs Archives of Pharmacology” These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.
26 citations
,
March 2014 in “Arquivos Brasileiros De Endocrinologia E Metabologia” This review discusses the definition, causes, diagnostic strategies, and treatment options for hirsutism in women without reporting new clinical results, and highlights the impact of the condition on self-esteem.
24 citations
,
November 2016 in “Molecular Medicine Reports” This study found that women with acne resistant to conventional treatments had significantly higher levels of testosterone, DHEA‑S, prolactin, and LH, suggesting potential underlying hormonal disorders.
22 citations
,
January 1979 in “JAMA” Minoxidil can lower blood pressure effectively and safely in emergencies.
20 citations
,
February 1977 in “Circulation” Minoxidil lowers blood pressure and increases heart efficiency, but may raise lung artery pressure in some people.
15 citations
,
April 2022 in “Biointerface Research in Applied Chemistry” This review presents current evidence on medicinal plants and their phytoconstituents, such as phenolic compounds, used in acne treatment, highlighting their potential as alternatives to conventional therapies due to issues like antibiotic resistance and high cost.
15 citations
,
June 2019 in “Journal of Neuroendocrinology” This study found that isoallopregnanolone reduced stress-induced tic-like behaviors and sensorimotor gating deficits in a mouse model of Tourette syndrome, suggesting potential therapeutic properties comparable to existing treatments like haloperidol and finasteride.
15 citations
,
November 2002 in “Cardiology in Review” This review discusses various adverse skin reactions linked to cardiovascular medications and reports no new clinical results, highlighting the need for vigilance when prescribing these drugs.
12 citations
,
December 2022 in “Annals of Phytomedicine An International Journal” This review discusses the historical and potential medical uses of Cyperus rotundus rhizomes, but reports no new clinical results and emphasizes the need for further study on its pharmacognostic properties.
10 citations
,
May 1995 in “Journal of General Internal Medicine” Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.
7 citations
,
January 2019 in “Brazilian Journal of Pharmaceutical Sciences” This study found that Adiantum capillus-veneris extract exhibited significant antidepressant and anti-anxiety effects in rats, likely due to its antioxidant and anti-inflammatory properties.
4 citations
,
August 2017 in “The Nurse Practitioner” This article discusses the systematic diagnostic evaluation of secondary amenorrhea and provides guidance for referral considerations; it reports no new research findings.
3 citations
,
November 2020 in “Biological Trace Element Research” This study found that patients with androgenetic alopecia had deficiencies in certain trace elements and vitamins, which were linked to distinct patterns of hair loss connected to androgen levels.
3 citations
,
January 2010 in “Actas Dermo-Sifiliográficas” This paper reviews the growing use of psychotropic drugs in dermatology due to the link between mental states and skin conditions but does not present new clinical findings.
2 citations
,
January 2017 in “Clinical and medical investigations” This research reports that herb lotions for alopecia areata, particularly those containing salvia miltiorrhiza radix, were effective in promoting hair regrowth in 64.8% of severe cases, akin to DNCB and SADBE.
1 citations
,
September 2022 in “Problems of Endocrinology” This review discusses sex differences in Parkinson's disease and highlights that while men are more frequently affected, androgen-modulating treatments have not yet proven effective for PD, though 5α-reductase inhibitors show potential for further study.