419 citations
,
May 2002 in “British journal of dermatology/British journal of dermatology, Supplement” This study reports cases of arterial embolization occurring due to the injection of hyaluronic acid (Restylane®).
239 citations
,
September 1996 in “The journal of alternative and complementary medicine/Journal of alternative and complementary medicine” Traditional African medicinal plants should be scientifically tested and integrated into modern healthcare.
202 citations
,
January 1989 in “Journal of Clinical Investigation” This study indicates that insulin changes sex hormone levels in insulin-resistant women with polycystic ovary syndrome without affecting gonadotropin release, challenging the idea that hyperinsulinemia directly causes hyperandrogenism in PCO.
158 citations
,
February 2012 in “Journal of Investigative Dermatology” FGF18 helps keep hair in its resting phase, affecting hair growth cycles.
120 citations
,
November 2014 in “Biological Reviews” This article explores the dynamic and energy-efficient nature of telogen hair follicles, challenging the notion of dormancy, and highlights their potential in advancing treatments for hair growth disorders.
116 citations
,
April 2002 in “American journal of veterinary research” This study found trilostane to be an effective and generally safe treatment for improving symptoms in dogs with pituitary-dependent hyperadrenocorticism.
106 citations
,
June 2005 in “Journal of Investigative Dermatology” This study defines classification criteria for hair follicle dystrophy using a mouse model of chemotherapy-induced alopecia, providing tools for standardized hair damage assessment.
69 citations
,
April 2005 in “Forensic Science International” This study suggests that degraded human hair shafts are highly resistant to contamination by exogenous DNA, making them a valuable source for forensic and ancient DNA analysis.
68 citations
,
May 2015 in “Indian Journal of Dermatology” This case series found that adding microneedling to conventional finasteride and minoxidil therapy for androgenetic alopecia improved new hair growth and patient satisfaction in poor responders.
61 citations
,
September 2024 in “Micromachines” This paper provides a comprehensive overview of the applications of electrospun nanofibers in non-invasive medical fields, highlighting their potential for health monitoring, personal protection, thermal regulation, and wound care, and discusses the challenges and future development paths for this technology.
60 citations
,
January 2021 in “BMC Genomics” This study mapped genomic copy number variation in Chinese fine-wool sheep, identifying genes involved in sensory perception, nutrient metabolism, growth, and development, and highlighting significant selection on the RXFP2 gene.
57 citations
,
December 2011 in “Lasers in Surgery and Medicine” This study suggests that selective photothermolysis of sebaceous glands using free electron laser pulses may offer a novel approach to treating acne by causing targeted thermal damage without affecting the epidermis.
55 citations
,
March 2012 in “Journal of Investigative Dermatology” Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
54 citations
,
October 2007 in “The FASEB Journal” This study suggests that hairlessness in nude mice may be due to insufficient expression of phospholipase C-δ1, a molecule essential for normal hair development downstream of the Foxn1 gene.
52 citations
,
January 1999 in “Journal of Small Animal Practice” This case study of a cat with pancreatic carcinoma and paraneoplastic alopecia found that removing the internal tumor reversed hair loss, but symptoms reappeared as the cancer metastasized.
50 citations
,
May 2021 in “Frontiers in immunology” This review discusses how tissue resident memory T cells contribute to autoimmune skin diseases like vitiligo and psoriasis, highlighting their role in continuous immune activation, and reports no new clinical results.
47 citations
,
June 2013 in “Biology of blood and marrow transplantation” This study presents a new mouse model for investigating chronic graft-versus-host disease, highlighting the role of human thymic tissue in developing multiorgan fibrosis driven by human immune cells.
44 citations
,
August 2012 in “Journal of Food Science” This study optimized conditions for extracting saponins from Eclipta prostrata, achieving maximum yield with specific ethanol concentration, time, temperature, and liquid/solid ratio.
42 citations
,
February 2017 in “Dermatologic surgery” This study found that VYC-15L (Juvéderm Volbella XC) was safe and effective for enhancing lip and perioral areas, achieving higher lip fullness improvement and fewer severe injection site reactions compared to NASHA, with effects lasting up to one year.
40 citations
,
February 2002 in “International Journal of Dermatology” In this study, hair damaged by permanent dye showed signs of recovery over time, with near complete restoration to its original state after eight weeks.
37 citations
,
October 2017 in “Advanced drug delivery reviews” This review explores the mechanisms of skin repigmentation and therapeutic strategies for pigmentation disorders following burn injuries, but it presents no new clinical results.
36 citations
,
October 2021 in “Frontiers in Endocrinology” This study highlights the importance of understanding the roles of hyperandrogenemia and insulin resistance in the development and progression of PCOS, emphasizing further research to clarify their mutual influence.
36 citations
,
February 2021 in “Clinical Nutrition” This study found that resveratrol improved menstrual regularity and reduced hair loss in women with PCOS, but did not affect androgen levels or metabolic profiles.
31 citations
,
August 2019 in “Regenerative Medicine” This study found that the human placenta extracellular matrix hydrogel restored the hair-inductive capacity of high-passaged dermal papilla cells, enabling them to regenerate new hair follicles when co-grafted with mouse epidermal cells.
31 citations
,
November 2013 in “Dermatologic Clinics” This article discusses the use of a robotic system for hair graft harvesting in hair restoration surgery, focusing on its capabilities and the advantages and disadvantages, but it reports no new clinical findings.
30 citations
,
November 2020 in “Journal of Advanced Research” This study found that conditioned medium from keratinocytes improved the hair-inductive properties of cultured dermal papilla cells, suggesting potential for enhancing hair follicle regeneration.
30 citations
,
September 2017 in “Environmental health perspectives” This study found that potential exposure to Corexit™ dispersants during the Deepwater Horizon cleanup was associated with increased respiratory, dermal, and eye irritation symptoms among responders both during the cleanup and up to three years later.
30 citations
,
July 1984 in “Journal of Animal Science” In this study, sows fed a diet with added biotin weaned more pigs per litter overall, though other reproductive and health metrics showed no improvement.
29 citations
,
February 2013 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that Merkel cell clusters require Frizzled6 signaling for their polarity information, while other hair follicle-associated structures align their orientation based on the hair follicle itself.
29 citations
,
January 2004 in “Experimental Dermatology” In this study, anthralin treatment led to hair regrowth in alopecia areata-like affected C3H/HeJ mice, suggesting it may be an effective therapy for this condition.