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    Glossary Cell Reprogramming

    process of converting specialized cells into stem cell-like states

    Cell Reprogramming, also known as Cellular Reprogramming, is a process where specialized cells, such as skin cells, are converted back into a more primitive, stem cell-like state. This is typically achieved by introducing specific genes or proteins that reset the cell's identity, allowing it to potentially develop into different types of cells. This technique holds significant promise for regenerative medicine, including treatments for conditions like alopecia, where new hair follicles could be generated from reprogrammed cells.

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    Research 30 of 1000+

    1. Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin Development · 2011 · 128 citations
    2. MicroRNA-302 Increases Reprogramming Efficiency via Repression of NR2F2 Stem cells · 2012 · 123 citations
    3. Cellular plasticity in reprogramming, rejuvenation and tumorigenesis: a pioneer TF perspective Trends in Cell Biology · 2023 · 45 citations
    4. Reprogramming of Human Hair Follicle Dermal Papilla Cells into Induced Pluripotent Stem Cells Journal of Investigative Dermatology · 2012 · 26 citations
    5. Reprogramming of three-dimensional microenvironments for <i>in vitro</i> hair follicle induction bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 1 citations
    6. Reprogramming of Aged Dermal Papilla Cells in Vitro: In Silico Insight into the Biomarkers of Hair Growth and Tissue Repair Preprints.org · 2025
    7. Reprogramming the wound microenvironment: identity remodeling strategies for fibroblasts, keratinocytes, and macrophages Frontiers in Immunology · 2026
    8. Reprogramming of human keratinocytes into functional cardiomyocytes Italian Journal of Anatomy and Embryology · 2026
    9. Reprogramming Wound Healing: GAG ‐Based Bioactive Scaffold Drives Pro‐Regenerative Cellular Cross‐Talk Journal of Biomedical Materials Research Part B Applied Biomaterials · 2026
    10. Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth Proceedings of the National Academy of Sciences of the United States of America · 2013 · 256 citations
    11. Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells Nature · 2010 · 116 citations
    12. Microenvironmental reprogramming of human dermal papilla cells for hair follicle tissue engineering Acta Biomaterialia · 2022 · 45 citations
    13. A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming Experimental and Molecular Medicine · 2018 · 19 citations
    14. Inflammatory memory-activated biomimetic nanovesicles regulate neutrophil plasticity and metabolic reprogramming for rapid diabetic wound healing via targeting miR-193a-5p/TLR4/JNK/P38 MAPK pathways Journal of Nanobiotechnology · 2025 · 9 citations
    15. Lineage potential, plasticity and environmental reprogramming of epithelial stem/progenitor cells Biochemical Society Transactions · 2014 · 4 citations
    16. Direct Reprograming of Mouse Fibroblasts into Dermal Papilla Cells via Small Molecules International Journal of Molecular Sciences · 2022 · 3 citations
    17. Modern Polycystic Ovary Syndrome (PCOS) Management: Intelligent Drug Delivery and Metabolic Reprogramming for Ovarian Restoration and Fertility Optimization Biomolecules · 2026
    18. Nanotechnological reprogramming of the pathological skin microenvironment in scar formation and atopic dermatitis Journal of Pharmaceutical Investigation · 2026
    19. Engineered Bilayer Hydrogel with Spatiotemporal Drug and Oxygen Delivery for Diabetic Wound Microenvironment Reprogramming Regenerative Biomaterials · 2025
    20. Direct reprogramming of human fibroblasts into hair-inducing dermal papilla cell-like cells by a single small molecule Biochemical Pharmacology · 2025
    21. Mitochondrial Dysfunction in Lichen Planopilaris with Focus on Oxidative Stress and Metabolic Reprogramming International journal of research studies in biosciences · 2025
    22. Diabetes Mellitus Inhibits Hair Follicle Regeneration by Inducing Macrophage Reprogramming-Mediated Pyroptosis Journal of Inflammation Research · 2024
    23. Regulation of somatic cell reprogramming through inducible mir-302 expression Nucleic acids research · 2010 · 308 citations
    24. Hypoxia in Cell Reprogramming and the Epigenetic Regulations Frontiers in Cell and Developmental Biology · 2021 · 36 citations
    25. Direct cellular reprogramming enables development of viral T antigen–driven Merkel cell carcinoma in mice 2022 · 14 citations
    26. Metabolic and transcriptomic reprogramming during contact inhibition-induced quiescence is mediated by YAP-dependent and YAP-independent mechanisms Nature Communications · 2024 · 11 citations
    27. Small RNAs Loom Large During Reprogramming Cell stem cell · 2011 · 18 citations
    28. Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea Science Advances · 2022 · 16 citations
    29. 1497 Type 2-mediated oxidative reprogramming promotes the transition of macrophages into repair mode and is required for wound healing Journal of Investigative Dermatology · 2023
    30. Faculty Opinions recommendation of Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2013