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Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

New treatments for male hypogonadism are effective and should be personalized.

Women with PCOS often experience anxiety, depression, and a lower quality of life.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Women with PCOS have lower ghrelin levels and a weaker response to sugar, which might affect their feeling of fullness and lead to overeating.

Mice with human gene experienced hair loss when treated with DHT.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

Quercetin may help with PCOS symptoms, but more research is needed.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Women with excessive male-pattern hair growth should get a full hormone check-up to find and treat any underlying issues, considering both medical and emotional aspects.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.

GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.

The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.

Men with male pattern baldness have a higher risk of dying from prostate cancer.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.