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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Nerves are crucial for the regeneration of various body parts in many animals.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Stem cell niches support, regulate, and coordinate stem cell functions.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Humans lost body hair relatively recently in evolution.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Finasteride effectively blocks enzyme causing male pattern baldness.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.