75 citations
,
November 1996 in “Fertility and Sterility” This study found that finasteride effectively reduced hirsutism in women during 12 months of treatment, with some effects persisting in the majority after stopping the medication.
21 citations
,
November 2015 in “Archives of Gynecology and Obstetrics” Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.
1 citations
,
July 2018 in “Current Sexual Health Reports” This review discusses the occurrence of persistent sexual, physical, neurological, and psychiatric side effects known as post-finasteride syndrome after 5x-reductase inhibitor treatment, and emphasizes the importance of evaluating these risks for patients with benign prostatic hyperplasia or androgenic alopecia.
April 2023 in “Clinical theriogenology” This report highlights the usefulness of specific diagnostic procedures, including penile/preputial cytology and transabdominal ultrasonography, in diagnosing cryptorchidism and Sertoli cell tumors in dogs with generalized skin conditions.
62 citations
,
December 2015 in “Clinical Medicine” This review discusses the relationship between obesity and PCOS, highlighting the potential of weight loss and improved insulin sensitivity to alleviate associated symptoms, and suggests the exploration of new therapies targeting weight management.
12 citations
,
August 2011 in “European Journal of Endocrinology” This study found that anti-Müllerian hormone (AMH) is a valuable primary variable for classifying functional androgenization, especially in distinguishing ovarian-related groups, and supports the novel stratification system.
1 citations
,
December 2015 in “Endocrinology” This study suggests that dietary decanoic acid may manage hyperandrogenism and insulin resistance in PCOS, as observed in animal and cell model experiments.
September 2022 in “International Journal of Health Sciences and Research” In this study, both resistance training and aerobic exercise with lifestyle modification were similarly effective for managing PCOS symptoms, but resistance training showed more significant benefits for BMI and menstrual regularity.
June 2024 in “Kushtia Medical College Journal” This observational study conducted at Kushtia Medical College explored the socio-demographic and clinical profiles of 100 women with PCOS, highlighting that a significant number of these patients experienced infertility, dysmenorrhea, and metabolic abnormalities, suggesting a need for timely therapeutic interventions.
124 citations
,
June 2002 in “Best Practice & Research Clinical Endocrinology & Metabolism” This article reviews polycystic ovary syndrome in adolescents, highlighting its endocrine and metabolic features, and reports no new clinical findings; the etiology may involve early-life abnormalities in androgen production.
89 citations
,
November 2014 in “Medical Clinics of North America” This article reviews management strategies for PCOS and reports no new clinical results; the authors highlight oral contraceptives, lifestyle modifications, and metformin as key interventions.
49 citations
,
November 2019 in “Egyptian Journal of Medical Human Genetics” This review discusses the role of CYP gene polymorphisms in exacerbating hyperandrogenism in women with PCOS and reports no clinical results; further validation of this hypothesis is needed.
20 citations
,
December 2000 in “Fertility and Sterility” This study found that the N363S variant of the glucocorticoid receptor was rare among women with PCOS and did not significantly contribute to genetic risk for PCOS or adrenal androgen excess.
11 citations
,
January 2013 in “Indian Journal of Endocrinology and Metabolism” This case study describes an extremely rare instance of androgen-secreting adrenocortical carcinoma in a patient with non-classical congenital adrenal hyperplasia.
10 citations
,
June 2010 in “Fertility and Sterility” In this study, patients with polycystic ovary syndrome self-reported higher hirsutism scores compared to clinician assessments, but only clinician scores correlated with biochemical markers of hyperandrogenism.
5 citations
,
May 2019 in “Hormone and Metabolic Research” This study reported that in embryo transfer cycles for women with nonclassic 21-hydroxylase deficiency, dexamethasone use was associated with improved pregnancy rates, and maintaining a BMI below 23.36 kg/m² increased pregnancy probabilities.
2 citations
,
January 2016 in “US Endocrinology” This study found that 27% of women with polycystic ovary syndrome reported perceived scalp hair thinning, which was associated with factors like advancing age, subjective hirsutism, disturbed sleep, smoking, abnormal glucose tolerance, and meal skipping.
2 citations
,
September 2004 in “Fertility and sterility” This review discusses the cosmetic and health implications of hirsutism and highlights its potential link to serious underlying disorders, but it presents no new clinical findings.
1 citations
,
August 2013 in “Springer eBooks” Birth control pills and anti-androgen medications help manage hair growth, acne, and hair loss in women with PCOS.
February 2024 in “Brazilian Journal of Implantology and Health Sciences” This review discusses the high prevalence of dermatological manifestations like hirsutism and acne in PCOS patients and explores various therapeutic approaches, highlighting the need for early recognition and treatment.
September 2022 in “Journal of Contemporary medical practice” This study found that among women with polycystic ovarian disease, 72% experienced infertility, indicating a correlation between PCOD and difficulties in conceiving.
April 2022 in “International Journal of Science and Research (IJSR)” This study found a correlation between polycystic ovarian disease and infertility among women, with 72% of participants experiencing difficulty conceiving.
February 2021 in “International Journal of Science and Research (IJSR)” This study found that the total testosterone/dihydrotestosterone ratio is significantly higher in women with polycystic ovary syndrome and is associated with a worse metabolic profile in both PCOS and healthy women.
June 2008 in “CRC Press eBooks” PCOS may have evolved as an advantage in past environments with food scarcity.
7 citations
,
October 2020 in “INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH” This study found that stress plays a significant role in altering phenotypic features and body composition among PCOS patients, potentially worsening due to the COVID-19 pandemic.
April 2024 in “International Journal of Advanced Multidisciplinary Research and Studies” This study outlines a multidisciplinary approach to investigate primary amenorrhea, emphasizing the necessity to consider medical history, physical examination, and potential hormonal or anatomical causes, and recommends early referral in cases of chromosomal abnormalities or persistent amenorrhea following the development of secondary sexual characteristics.
January 2020 in “International journal of current research and review” This study found that high exposure to plastics was associated with increased chances of irregular menstrual cycles and symptoms similar to polycystic ovary syndrome in adolescent girls.
72 citations
,
October 1998 in “Baillière's clinical endocrinology and metabolism” This article discusses the potential effects of exogenous testosterone, highlighting that its impact on prostate cancer progression, cardiovascular health, and behavior remains uncertain and needs further investigation.
14 citations
,
January 2018 in “Advances in Clinical Chemistry” This review discusses the evaluation of hyperandrogenemia in women and hypogonadism in men across different life stages and presents biomarkers used for diagnosing male hypogonadism, reporting no new clinical results.
11 citations
,
February 2013 in “Clinical Endocrinology” This study found that the prevalence of hyperprolactinaemia in healthy premenopausal female blood donors is low and not affected by hormonal contraceptive use, with stress-related factors being the most common cause.