221 citations
,
January 2014 in “Human Reproduction” This study found that the prevalence of polycystic ovary syndrome was 16.6% with Rotterdam criteria but decreased to 6.3% or 8.5% when using alternative criteria involving antral follicle count or anti-Müllerian hormone.
111 citations
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November 2010 in “Human Reproduction” This study found that young indigenous South Asian women with polycystic ovary syndrome are more likely to be centrally obese and have metabolic syndrome, particularly with increasing age, higher BMI, and acanthosis nigricans.
3 citations
,
August 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that women with PCOS had significantly elevated plasma levels of PAI-1, which correlated with insulin resistance and obesity.
68 citations
,
January 2008 in “Seminars in reproductive medicine” This narrative review discusses the impact of polycystic ovary syndrome on women's psychological and sexual well-being, highlighting the potential benefits of interdisciplinary treatments and new interventions to improve life satisfaction and coping, but reports no new results.
45 citations
,
January 2013 in “Journal of Human Reproductive Sciences” In this study, women with PCOS had a higher prevalence of hepatic steatosis compared to controls, with associated metabolic issues like insulin resistance and metabolic syndrome.
35 citations
,
October 2004 in “Biology of Reproduction” This study found that dual 5α-reductase inhibition in rats led to decreased sperm motility and altered morphology, resulting in subfertility.
28 citations
,
August 2014 in “Journal of Assisted Reproduction and Genetics” This study found that the VEGF +405G/C polymorphism may be an inheritable risk factor for polycystic ovary syndrome in south Indian women.
26 citations
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June 2016 in “Journal of Reproductive Immunology” This study found that in women with polycystic ovary syndrome, xanthine oxidase activity is a useful marker for oxidative stress and is positively correlated with inflammatory markers and cardiovascular disease risk factors.
10 citations
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April 2006 in “Seminars in Reproductive Medicine” This article reviews the limited evidence on testosterone therapy for premenopausal women and notes a lack of long-term safety and effectiveness data for this population.
9 citations
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June 2014 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Blood AMH levels are higher in women with PCOS than in those with other similar conditions.
5 citations
,
October 2016 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” This study found that women with PCOS had significantly prolonged nasal mucociliary clearance time, which may increase their susceptibility to respiratory tract and middle ear infections.
2 citations
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May 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” In this study, Myoinositol, an insulin sensitizer, was reported to improve menstrual irregularities and skin problems in cases of polycystic ovary syndrome.
1 citations
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January 2011 in “Journal of Human Reproductive Sciences” Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.
October 2025 in “International Journal of Reproduction Contraception Obstetrics and Gynecology” This study found that Myoinositol and D-chiro inositol treatment improved fertility outcomes in women with PCOS, particularly in Phenotypes A and D, but larger studies are needed to confirm these results.
July 2024 in “International Journal of Reproduction Contraception Obstetrics and Gynecology” This study found that infertile women with polycystic ovary syndrome in Ardabil had a significantly higher rate of depression compared to those without the condition, highlighting the need for attention to the mental health aspects of PCOS.
February 2023 in “Global Journal of Reproductive Medicine” The authors discuss BPH treatment options and highlight that while medications can manage symptoms, recent minimally invasive procedures may offer promise for elderly males who are not surgical candidates or wish to avoid surgery.
June 2018 in “Global Journal of Reproductive Medicine” This case report describes a 28-year-old woman with facial, abdominal, and thigh hirsutism who showed little improvement after 5 months of Metformin and spironolactone treatment.
January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that the IGF2 gene Apa1 A820G polymorphism is associated with an increased risk of developing PCOS in the studied population.
21 citations
,
January 2017 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” This study suggests that acne is often associated with hyperandrogenemia in women, contradicting previous recommendations that acne is not linked to androgen excess disorders.
7 citations
,
August 2017 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” This study found that lower serum vaspin levels (below 3.74ng/mL) may predict successful ovulation induction with clomiphene citrate in anovulatory women with PCOS, indicating potential resistance when levels are higher.
5 citations
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April 2014 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” This study concluded that antimullerian hormone levels are not generally effective for distinguishing late onset congenital adrenal hyperplasia from all hyperandrogenic polycystic ovary syndrome subtypes, except one specific subtype.
4 citations
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November 2012 in “Obstetrics, Gynaecology & Reproductive Medicine” This review describes therapeutic strategies for polycystic ovary syndrome, highlighting current treatments for ovulation induction and emphasizing lifestyle changes and personalized approaches, but reports no new clinical results.
7 citations
,
February 2019 in “Journal of gynecology obstetrics and human reproduction” Patients with Polycystic Ovary Syndrome in this study had significantly higher anxiety and depression scores compared to controls, but showed no significant differences in temperament and character traits.
April 2008 in “Obstetrics, gynaecology and reproductive medicine” This article reviews the diagnosis and management of hirsutism in women, discussing its causes, assessment, and treatment options; no new clinical findings are included.
9 citations
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January 2022 in “Reproductive Biology and Endocrinology” This study aimed to identify reliable predictors for the effectiveness of metformin therapy in weight loss and reduction of plasma androgen levels in PCOS women, highlighting the unpredictability of response to treatment.
14 citations
,
January 2025 in “Reproductive Medicine and Biology” This review emphasizes the importance of considering race and ethnicity-specific factors in diagnosing and treating polycystic ovary syndrome (PCOS) and calls for diagnostic criteria tailored to these differences.
3 citations
,
July 2025 in “Reproductive Biology and Endocrinology” This study found that chromium, inositol, and Omega-3 are beneficial for improving lipid profiles in women with PCOS, and various supplements help alleviate other symptoms.
2 citations
,
March 2021 in “Reproduction” This study found that finasteride may affect Ca 2+ signalling in human sperm by interacting with the PGE 1 -binding site, but its impact on fertilization requires further investigation.
1 citations
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May 2022 in “Reproductive Endocrinology” This review discusses the complexities of diagnosing and managing hyperandrogenism in women, emphasizing the need for careful evaluation of both clinical signs and biochemical markers without reporting new clinical results.
January 2024 in “Reproductive toxicology” This study found that hesperidin, a bioflavonoid, mitigated the negative effects of finasteride on sperm health and testicular structure in male Wistar rats by reducing oxidative stress and apoptosis and supporting testicular antioxidant capacity.