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Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Long-term estrogen therapy in postmenopausal women can improve certain health markers, hair loss is common regardless of hormone use, stopping estrogen doesn't increase breast cancer risk, smoking does, and a balanced BMI is linked to lower mortality.

3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Certain long non-coding RNAs are important for controlling hair growth cycles in sheep.

Licorice has many traditional health benefits, but more research is needed to fully support these claims.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Certain spices may help prevent and treat skin cancer, but more human trials are needed.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The conclusions are: fecal short-chain fatty acids may help prevent cancer, fiber intake can reduce obesity, weight loss is hard for obese people, low BMI cancer patients are more prone to chemotherapy side effects, intermittent fasting benefits gut health, cherry laurel has health benefits in rats, certain gene variations can increase stress in hair loss patients, fecal acids can affect blood sugar levels, cold agglutinin can affect blood test results in autoimmune patients, and people with Crohn's disease have higher levels of a certain chemical in their blood.

After chemotherapy for a gestational trophoblastic tumor, normal pregnancy rates are possible, but there's a slightly higher risk of the tumor reoccurring in future pregnancies.

Kangfuxin (KFX) extract speeds up wound healing and improves skin regeneration.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.