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Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Lindera aggregata has many beneficial compounds that can help prevent and manage diseases.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Gender identity can be more diverse than just male or female.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

Hormones affect prostate health and disease, with certain hormone imbalances linked to prostate cancer and benign prostatic hyperplasia.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Some herbs show promise as antiandrogenic agents.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Finger length ratios might predict risk for skin condition in males.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The document suggests that finasteride may cause depression and suicidal thoughts, while prostate surgery does not harm sexual health.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.

HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Understanding how acne develops in different diseases could lead to new treatments.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

CBD may improve skin and hair health, but its effective use and safety need more research.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

People with hair loss conditions may also have thyroid disorders, but more research is needed to understand the connection.

The review suggests a comprehensive approach to treat hirsutism, focusing on hair removal, medication, and managing emotional effects.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Targeting the skin's endocannabinoid system could help treat skin disorders.

One Ashwagandha extract may help protect cells with its antioxidant properties, while another could promote hair growth.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.