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Stem cell niches support, regulate, and coordinate stem cell functions.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

A new gene, JMJD1C, may affect testosterone levels in men.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Prolactin affects when mice shed and grow hair.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Neurosteroids show promise for treating epilepsy and more research is needed.

Lamins are vital for cell survival, organ development, and preventing premature aging.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.