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Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.

Polycystic ovary syndrome, a disorder causing menstrual issues and infertility, can be treated with lifestyle changes, medication, herbal remedies, surgery, and assisted reproductive techniques like artificial insemination and IVF.

The document concludes that managing PCOS involves lifestyle changes, medication, and monitoring for associated health risks.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

Eating a Mediterranean diet and taking certain supplements may improve symptoms of PCOS.

Measuring the distance from the anus to the clitoris may moderately help diagnose polycystic ovary syndrome, especially in certain cases.

Low-dose anti-androgen drugs and certain drug combinations are effective for hirsutism, and insulin sensitizers show promise, especially for those with polycystic ovarian syndrome.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.

Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.

Metformin effectively improves metabolic symptoms in women with PCOS, while alfacalcidiol does not have a significant impact.

The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

SHBG may be a useful early indicator and treatment target for PCOS.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

A certain gene variant may increase the risk of polycystic ovary syndrome in Chinese women.

Alfacalcidiol and metformin together lowered testosterone in women with PCOS, but did not significantly improve acne, hair growth, or pregnancy rates.

Hypothyroidism in dogs is usually caused by immune system issues or gland atrophy, affects middle-aged purebreds most, and is treatable with medication.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Managing emotional distress, obesity, insulin resistance, and high male hormones is crucial for improving well-being in women with PCOS.

Skin issues are common and important for diagnosing PCOS.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.