62 citations
,
August 2014 in “BMC Endocrine Disorders” This review summarizes the recent advances in molecular mechanisms influencing tissue sensitivity to glucocorticoids, emphasizing novel mutations and new information on the glucocorticoid receptor's circadian rhythm and ligand-induced repression, but reports no new results.
62 citations
,
December 2013 in “Aaps Journal” This research reported that squarticles, nanoparticles made from sebum-derived lipids, enhanced the follicular delivery and skin accumulation of diphencyprone and minoxidil, indicating effective drug deposition with reduced systemic absorption in alopecia treatment.
61 citations
,
June 2022 in “IEEE Journal of Biomedical and Health Informatics” This study introduced a novel deep clustering approach for melanoma detection from dermoscopic images, demonstrating improved performance over existing methods by mitigating class imbalance issues using a center-oriented margin-free triplet loss.
58 citations
,
March 2013 in “Human Reproduction Update” This review discusses various substances that can impact male fertility and stresses that products should be confirmed 'sperm-safe' through rigorous testing, not assumptions; it reports no new study results.
57 citations
,
November 2017 in “Nature Communications” This genome-wide association study identified 71 genetic loci linked to male pattern baldness, with 30 novel loci, explaining 38% of the risk and suggesting shared pathways with lifespan and cancer traits.
52 citations
,
January 2020 in “Scientific Reports” This study found that nanostructured lipid carriers with clobetasol propionate significantly enhance follicular drug delivery compared to commercial cream, and manual massage further doubles follicular retention.
49 citations
,
April 2016 in “International journal of molecular sciences” This study found that shift nurses exhibited lower circadian variations compared to daytime nurses, indicating an adjustment of their biological clocks to continuous shift schedules.
48 citations
,
January 2018 in “Scientific Reports” This pilot study found that hair metabolome analysis may help differentiate pregnancy complications from healthy pregnancies by revealing significant metabolite differences between trimesters.
46 citations
,
December 2001 in “Journal of Endocrinology/Journal of endocrinology” This study found that mouse FLRG protein, a secreted glycoprotein, is expressed in certain tissues and plays a role distinct from follistatin during wound healing, suggesting different functions in vivo.
45 citations
,
June 2008 in “Journal of pharmaceutical and biomedical analysis” This study developed a new HPLC method for detecting prohibited substances like minoxidil and hydrocortisone in cosmetic products, achieving high sensitivity and successful application to real-world samples.
43 citations
,
November 2018 in “Nature Communications” This genome-wide association study identified 20 genetic signals at 15 risk loci related to severe acne, revealing new insights into its genetic predisposition, particularly affecting skin structure and maintenance.
36 citations
,
March 2002 in “Journal of Biological Chemistry” Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.
35 citations
,
May 2021 in “Nature communications” This study found that basement membrane components and structures in mouse hair follicles are highly specialized for specific inter-tissue interactions, with laminin α5 playing a crucial role in hair cycle regulation and anchoring.
35 citations
,
October 2015 in “International Journal of Pharmaceutics” Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.
34 citations
,
July 2011 in “Journal of Dermatological Treatment” This study found that a combination of 5% hexane extract of Curcuma aeruginosa and 5% minoxidil slowed hair loss and increased hair growth in men with androgenetic alopecia.
33 citations
,
January 2017 in “Conservation physiology” This study found that measuring reproductive hormone levels in brown bear hair may effectively support non-invasive genetic sampling, though larger samples or more sensitive techniques are needed for broader application.
33 citations
,
November 2008 in “European Journal of Pharmaceutical Sciences” This study found that St. John's wort treatment for two weeks induced finasteride metabolism and reduced its plasma exposure in healthy men.
32 citations
,
June 2012 in “PLoS ONE” This study found that locally injected zalutumumab in healthy volunteers induced a papulopustular rash similar to systemic EGFR inhibitors, and that IL-8 inhibition reduced this dermatological side effect.
29 citations
,
January 2021 in “Translational Psychiatry” This study found that certain gene sets, including those involved in ligand-gated ion channel signaling and cell adhesion, are associated with Tourette syndrome, suggesting a potential neurobiological basis for the disorder.
22 citations
,
November 2016 in “Indian Journal of Pharmaceutical Education and Research” This study found that ethanolic leaves extract of Hibiscus rosa-sinensis L. exhibited strong antioxidant activity and enhanced wound healing properties in mice, showing reasonable safety in toxicological evaluations without severe alterations.
21 citations
,
April 2018 in “Journal of Dermatological Science” This study found that topical cilostazol promotes hair growth, enhances hair follicle activities, and may serve as a potential treatment for alopecia.
19 citations
,
November 2023 in “npj Regenerative Medicine” This study found that synthetic melanin particles applied topically in mouse injury models improved wound healing, showing potential as a therapy for accelerated healing, including in human skin explants.
18 citations
,
January 2015 in “Data series” This report describes a study of estuarine bed-sediment quality in New Jersey and New York post-Hurricane Sandy, focusing on contamination extent and potential long-term impacts, with no new findings included.
18 citations
,
January 2008 in “Journal of The American Academy of Dermatology” This study found that the proteins GDNF, NTN, GFRα-1, GFRα-2, and c-Ret are differentially expressed during various stages of the human hair follicle cycle, with potential implications for hair biology.
14 citations
,
June 2014 in “Journal of Pharmaceutical Sciences” This study validated the differential stripping technique on hairless rat skin and found that the P-08–016 formulation delivered more finasteride to the epidermis and appendages compared to P-10–008.
13 citations
,
July 2019 in “Toxicology research” In this study, ethanamizuril was found to cause alopecia, biochemical changes, and organ damage at higher doses in rats, with a no-observed-adverse-effect level of 20 mg/kg over 30 days.
13 citations
,
September 2010 in “Journal of Dermatological Science” Researchers made a cell line that grows quickly and can help with hair growth research.
13 citations
,
November 2006 in “E-journal of Chemistry” This study developed a rapid and sensitive HPLC method for measuring finasteride in bulk and tablet forms, showing high precision and accuracy compared to the official method.
12 citations
,
April 2023 in “Nano Biomedicine and Engineering” This study synthesized silver nanoparticles using an Artocarpus heterophyllus leaf extract and found that these nanoparticles, with a size of 100–110 nm, displayed effective antioxidant, antibacterial, and antifungal activities in vitro.
11 citations
,
July 2017 in “Regenerative Medicine” This study found that the patch assay effectively reconstituted mature hair follicles using culture-expanded human fetal cells and may serve as a method to assess cell trichogenicity.