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Most children with CNS tumors on targeted therapy had skin reactions, which were generally treatable without stopping the therapy.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

TICE salvage chemotherapy is effective for treating germ-cell tumors with poor prognosis.

Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.

Activated ras can protect kidney cells from a certain substance that causes cell death.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

FDG PET/CT scans can change cancer treatment plans for dogs.

The document concludes that various skin conditions have specific treatments, ranging from antihistamines for urticaria to surgery and medication for tumors and chronic skin diseases.

The conclusion is that accurately identifying folliculosebaceous tumors requires understanding their clinical signs and microscopic features.

Kidney cancer cells without folliculin are more sensitive to radiation due to increased self-eating cell death.

A young woman with kidney cancer experienced rare hair loss from a cancer drug and unusual cancer spread, suggesting early drug treatment might reduce spread and prolong survival.

Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.

Ovarian vein sampling helped diagnose rare ovarian tumors causing high testosterone, and surgery to remove the tumors lowered the testosterone levels.

Ovarian steroid cell tumors should be considered in adults with hirsutism and high testosterone, with surgery as the main treatment.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

A COVID-19 infected patient with chronic kidney disease experienced worsened kidney function, hair loss, and unexpected wart clearance.

MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.

The document concludes that HAIR-AN syndrome should be considered when a patient shows severe hyperandrogenism and insulin resistance after excluding tumors.

MRI helps distinguish between pituitary adenomas and craniopharyngiomas, guides treatment for pediatric CNS tumors, and assesses rhinocerebral mucormycosis with a high mortality rate in transplanted patients.

Tjalma Syndrome is a rare condition in people with lupus, causing fluid buildup and high CA-125 levels, but not due to tumors.

Mannitol diuresis allows higher doses of cis-platinum for testicular cancer treatment without increasing kidney damage.

This is the first known case of parathyroid cancer in a patient with Birt Hogg Dube Syndrome.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

A woman with anorexia developed gout from self-induced vomiting.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Inactive hair follicle stem cells help prevent skin cancer.