research Chronic Tophaceous Gout Secondary to Self-Induced Vomiting in Anorexia Nervosa
A woman with anorexia developed gout from self-induced vomiting.
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research Persistent Wound Healing Disorders After Local Therapy of Scalp Field Cancerization with Imiquimod or Diclofenac
Older men with scalp wounds had long-term healing problems after using imiquimod or diclofenac for skin cancer prevention.
research Neoadjuvant Therapy With Disitamab Vedotin in Treating Muscle-Invasive Bladder Cancer: A Case Report
A 68-year-old man with muscle-invasive bladder cancer (MIBC) and severe renal insufficiency, who was ineligible for cisplatin-based treatment, was successfully treated with neoadjuvant therapy using gemcitabine and Disitamab Vedotin (DV). The patient received three cycles of gemcitabine 1600 mg and DV 120 mg intravenously every three weeks. Imaging results showed a significant reduction in lesions, indicating a radiological partial response. Throughout the treatment, no significant adverse side effects were observed, making this combination a viable alternative for patients unable to tolerate platinum-based regimens.
research Minoxidil in Severe Hypertension: Value When Conventional Drugs Have Failed
Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.
research Safety of Treatment Options for Spondyloarthritis: A Narrative Review
Most treatments for spondyloarthritis are safe, but monitoring and careful selection based on patient risks are important.
research Drug Safety Evaluation of Exemestane
Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.
research The Spectrum of Nephrocutaneous Diseases and Associations
Skin doctors should know about skin and kidney disease links to prevent serious kidney problems.
research The Prevalence of Itch and Pain and Its Characteristics in Patients with Mild to Moderate Venous Insufficiency and Its Relationship to the Degree of Venous Insufficiency
Itch is a common symptom in patients with chronic venous insufficiency, often accompanied by burning and pain.
research Alopecia in Three Women of Southeast Asian Descent with Chronic Renal Failure: Possible Association with Erythropoietin Use
Hair loss in three Southeast Asian women with kidney failure may be linked to their anemia treatment with erythropoietin.
research Protective Cardiovascular and Renal Actions of Vitamin D and Estrogen
Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.
research Calcineurin-Based Immunosuppression in Renal Transplantation: Focus on Efficacy, the Role of Steroids, and Cardiovascular Risk
Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.
research Minoxidil in Severe Hypertension with Renal Failure
Minoxidil effectively lowers blood pressure without major side effects.
research Severe Hypertension in Children With Renal Disease: Treatment With Minoxidil
Minoxidil lowers blood pressure in kids with kidney issues, but use carefully due to side effects.
research Long-Term Clinical Effects, Bioavailability, and Kinetics of Minoxidil in Relation to Renal Function
research Ranitidine And Finasteride Inhibit The Synthesis And Release Of Trimethylamine N-Oxide And Mitigate Its Cardiovascular And Renal Damage Through Modulating Gut Microbiota
Ranitidine and finasteride lower TMAO levels, reducing heart and kidney damage by changing gut bacteria.
research Prevalence of Itch and Pain in Patients with Mild to Moderate Chronic Venous Insufficiency at Parkland Memorial Hospital (2005)
Itch is a common symptom in patients with chronic venous insufficiency, often worsening with standing or sitting and occurring mostly in the evening or at night.
research Skin Manifestations in Patients with Chronic Renal Failure on Regular Hemodialysis
Patients on long-term hemodialysis often experience severe itching and various skin and nail problems.
research Growth Hormone Deficiency with Late-Onset Hypothalamic Hypoadrenocorticism Associated with Respiratory and Renal Dysfunction: A Case Report
A woman with childhood growth hormone deficiency had multiple hormone deficiencies and developed serious lung and kidney problems later in life.
research Development of a Non-Parametric Population Pharmacokinetics Model and Bayesian Estimator for Tacrolimus in Tunisian Renal Transplant Patients
The model and estimator can predict drug exposure in kidney transplant patients well.
research The Pharmacology of Methotrexate
Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.
research Flares of Systemic Lupus Erythematosus During Pregnancy and the Puerperium: Prevention, Diagnosis, and Management
Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.
research The Successful Treatment of Nephrogenic Fibrosing Dermopathy with Mycophenolate Mofetil
Mycophenolate mofetil improved skin condition in a man with nephrogenic fibrosing dermopathy.
research Aldesleukin
Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.
research Adverse Health Effects of Androgen Use
Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
research Rheumatologic Manifestations of Pregnancy
Pregnancy can cause symptoms similar to rheumatic diseases, making diagnosis difficult, and affects various body systems, requiring careful distinction between normal changes and serious conditions.
research Spironolactone
Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.
research Comprehensive Overview of Rheumatology Studies: Ottawa, Ontario, Canada, February 13–16, 2013
The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.
research 69-Year-Old Man With Nasal Congestion and Pre-Syncope
A 69-year-old man with sinus infection and fainting spells was diagnosed with a rare kidney disease, treated with steroids and a specific drug, which improved his condition.
research Late-Onset Systemic Lupus Erythematosus
Older adults diagnosed with lupus show less severe symptoms but have a lower survival rate, often due to age-related factors.
research Direct Vasodilators and Sympatholytic Agents
Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.