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Botulinum toxin injections effectively relieve pain from cutaneous leiomyomas.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

The document is a detailed medical reference on skin and genetic disorders.

Chemotherapy can cause skin issues and hair loss, and this guide explains how to manage them.

A man with kidney tumors and lung cysts was diagnosed with Birt–Hogg–Dubé syndrome and treated successfully, with genetic testing confirming the diagnosis.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

New cancer treatments are more precise and less toxic, improving survival rates, but Asia faces challenges in adopting these advancements.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Kidney cancer cells without folliculin are more sensitive to radiation due to increased self-eating cell death.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.

Birt–Hogg–Dubé syndrome is a rare genetic condition causing skin lesions, lung cysts, and a higher chance of kidney cancer.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.

Etoposide is effective in treating several cancers, especially small cell lung cancer, with acceptable side effects.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Cancer treatments targeting specific cells often cause skin, hair, and nail problems, affecting patients' lives and requiring careful management.

The document lists various dermatology topics, treatments, and diagnostic methods.

Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.

Hair loss in cancer patients can be related to the cancer itself, treatment, or other conditions, and understanding it is important for diagnosis and patient care.

Spanish experts provided guidelines for treating skin side effects in cancer patients on new therapies, stressing early action and teamwork.