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Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

The vitamin D receptor can work without its usual activating molecule.

Licorice root-derived nanoparticles target liver cancer cells to improve treatment and reduce side effects.

The 2012 criteria are better for diagnosing atypical lupus cases.

Hair loss linked to kidney stones in people under 60.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.

Most children with CNS tumors on targeted therapy had skin reactions, which were generally treatable without stopping the therapy.

A patient with myotonic dystrophy had several autoimmune disorders and thyroid cancer, suggesting a possible link between these conditions.

New targeted cancer drugs can cause skin side effects, and managing them requires patient education and timely care.

Some drugs can cause reversible hair loss, but certain chemotherapy drugs may lead to permanent hair loss; drugs can also change hair color and texture.

Targeted cancer therapies can cause skin side effects, which should be treated early to help patients' quality of life and treatment adherence.

The conclusion is that individualized treatment and proper medication use are crucial in men's health, with specific recommendations for ED, BPH, and prostate cancer management.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

A 37-year-old male with severe skin and internal issues has a rare inherited skin condition called dystrophic epidermolysis bullosa.

Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.

Cancer survivors often experience worse skin problems from treatment than expected, and working with dermatologists could help improve their condition.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Every elderly patient had at least one skin condition, often linked to other diseases, highlighting the need for integrated skin and general healthcare in the elderly.

A man got six skin cancers within a year after a cell transplant for leukemia but was cancer-free 32 months later; skin checks are important post-transplant.

Photodynamic therapy is the preferred treatment for skin precancer due to its effectiveness and safety.

BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.

Intralesional chemotherapy with 5-fluorouracil and methotrexate may worsen keratoacanthoma-type skin cancer in transplant patients.

Origanum vulgare leaf extract reduces liver and kidney damage caused by finasteride in mice.

Some blood pressure medications are linked to a higher risk of skin cancer.

The book concludes that despite progress, cancer drug treatments have not met the expectations set in the 1960s and 1970s.

Early recognition and management of skin side effects from new cancer therapies can prevent treatment delays.