research Clinical Development of Topoisomerase-Interactive Drugs
New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.
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research Comparative Efficacy and Safety of Janus Kinase Inhibitors Used in Alopecia Areata: A Systematic Review and Meta-Analysis
Baricitinib and deuruxolitinib are effective for treating alopecia areata, but their efficacy depends on the dose.
research Alopecia Universalis in an Adolescent Successfully Treated with Upadacitinib: A Case Report and Review of the Literature on the Use of JAK Inhibitors in Pediatric Alopecia Areata
A 14-year-old girl with severe hair loss regrew her hair using upadacitinib.
research Presentation, Diagnosis, and Management Options of Lipedematous Alopecia
Lipedematous alopecia involves a thickened scalp and hair loss, with limited effective treatments available.
research Balance of Tofacitinib Efficacy and Disease Flare in the Treatment of Alopecia Universalis: A Case Report and Review of the Literature
Tofacitinib can temporarily improve hair growth in alopecia universalis, but its effectiveness may decrease over time.
research Bendamustine: An Old Drug in the New Era for Patients with Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia
Bendamustine, often combined with other drugs, is effective and less toxic for certain blood cancers, but less effective for young, fit patients with CLL.
research Ruxolitinib Found to Cause Eyelash Growth: A Case Report
Ruxolitinib treatment may cause eyelash growth.
research Erosive Pustular Dermatosis of the Scalp Following Topical Ingenol Mebutate for Actinic Keratoses
Two elderly men developed scalp inflammation after using a gel for skin lesions, which healed with treatment except for some permanent hair loss.
research A Screening Study on Dermatoses in Pregnancy
Most pregnant women experience skin changes, mainly increased pigmentation, and some develop pregnancy-related skin conditions and infections.
research Alopecia Areata: Good Response to Treatment with Fractional Laser in 5 Cases
Fractional laser treatment helped hair regrowth in patients with alopecia areata.
research Cutaneous Crohn's Disease Treated with Infliximab and 4 Years of Follow-Up
Infliximab improved skin and bowel symptoms in Crohn's disease but caused side effects and the disease returned after stopping treatment.
research Scalp Hair Loss After Transsphenoidal Adenomectomy in Patients With Acromegaly
More than half of patients who had acromegaly surgery experienced hair loss, with varying degrees of recovery.
research Versatile Use of Submental Tissue for Reconstruction of Perioral Soft Tissue Defects
Submental tissue is good for repairing mouth area skin with minimal scarring and good cosmetic results.
research Postmillennial Breast Cancer Photo-Narratives: Technologized Terrain
The document concludes that modern photo stories help represent and challenge how breast cancer affects women's identities and societal norms.
research Three Isolations of Chaetomium Globosum from Erythematous Epilation of Canine Skin
A dog's skin infection caused by the fungus Chaetomium globosum was effectively treated with ketoconazole.
research A Case of Interface Perianal Dermatitis in a Dog: Is This an Unusual Manifestation of Lupus Erythematosus?
A dog with unusual skin lesions near its tail was successfully treated for a rare form of lupus.
research A Primary Adrenal Non-Hodgkin's Lymphoma Presenting as an Incidental Adrenal Mass
A woman's small, unnoticed adrenal mass turned out to be a rare non-Hodgkin's lymphoma, treated successfully with surgery and therapy.
research Erosive Pustulosis of the Scalp: 3 Cases
Oral zinc and topical steroids can effectively treat chronic scalp pustules and hair loss in elderly patients.
research Anticytokine Therapy, Particularly Anti-IFN-γ, in Th1-Mediated Autoimmune Diseases
Blocking interferon-gamma might help treat various autoimmune diseases.
research Case Report: Pemphigus Vulgaris in an Adolescent
An 18-year-old girl with pemphigus vulgaris needed strong medication and careful treatment due to ineffective initial therapies and side effects.
research An Unusual Presentation of Dermatomyositis: The Type Wong Variant Revisited
A woman with a rare type of dermatomyositis improved with low-dose prednisone and methotrexate.
research Treatment of Androgen Excess in Females: Yesterday, Today, and Tomorrow
The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
research Profound Bradycardia After Addition of Diltiazem to a Beta Blocker
Adding diltiazem to a beta blocker can cause dangerously slow heart rates.
research Various Applications of Tofacitinib and Ruxolitinib in Dermatology and Rheumatology: A Review of Current Evidence and Future Perspective
Tofacitinib and ruxolitinib are effective and safe for treating various autoimmune skin and joint disorders.
research Pellagra and Anorexia Nervosa: A Case Report
A woman with anorexia nervosa improved after treatment for pellagra, reminding doctors to check for this deficiency in patients with eating disorders.
research Emerging Nonsteroid-Based Procedural Therapies for Alopecia Areata: A Systematic Review
Nonsteroid treatments for alopecia areata show promise but need more high-quality research.
research Treatment of Satoyoshi Syndrome: A Systematic Review
Corticosteroids are the most effective treatment for Satoyoshi syndrome.
research Excellent Short- and Medium-term Results of Bariatric Surgery in Adolescents: A Single Center Study
Bariatric surgery is safe and effective for treating adolescent obesity.
research Safety Profile of Finasteride: Distribution of Adverse Effects According to Structural and Informational Dichotomies of the Mind/Brain
Finasteride can cause sexual dysfunction and depression, which may persist and require hormonal treatment.
research Evaluation of Trichodynia During Chemotherapy or Tamoxifen Treatment in Breast Cancer Patients
Hair and scalp pain is more common and severe in breast cancer patients on chemotherapy than those on tamoxifen.