January 2026 in “International Journal of Medical and All Body Health Research” This study found that both intralesional corticosteroids (TAC) and platelet-rich plasma (PRP) are effective for treating patchy alopecia areata, with TAC providing faster early results but PRP offering better long-term safety and lower relapse rates.
This chapter reviews alopecia areata treatments, highlighting factors like age and disease extent in choosing management strategies, but reports no new clinical findings.
May 2023 in “Clinical and Experimental Dermatology” Alopecia areata has a high chance of persisting and relapsing, with a significant risk of total hair loss, especially if it starts in childhood.
January 2012 in “Current Therapy In Oral and Maxillofacial Surgery” Endoscopic forehead and brow lifting safely and consistently improves aged eyebrows, but may have complications.
32 citations
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July 2003 in “Annals of the Rheumatic Diseases” This case report describes the successful treatment of a 13-year-old girl's autoimmune symptoms with co-trimoxazole, an antibiotic with immunomodulatory properties.
8 citations
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July 2003 in “Annals of the Rheumatic Diseases” This case study describes the successful treatment of a 13-year-old girl with relapsing polychondritis and autoimmune symptoms using co-trimoxazole, highlighting its potential role in managing autoimmune diseases.
6 citations
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March 2016 in “Multiple sclerosis and related disorders” This case report describes a 55-year-old woman who experienced transient hair loss possibly linked to the start of dimethyl-fumarate therapy for relapsing-remitting Multiple Sclerosis.
5 citations
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August 2018 in “Neurology and Therapy” In this observational study, most patients with multiple sclerosis on teriflunomide who experienced hair thinning reported it as mild or moderate and largely recovered while continuing treatment.
This article reviews the spectrum of connective tissue disorders and discusses the role of autoantibodies, particularly in lupus erythematosus, but reports no new findings.
63 citations
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January 1971 in “Acta Medica Scandinavica” This study found that replenishment of iron stores after phlebotomy-induced remission in porphyria cutanea tarda led to biochemical relapse, suggesting that reducing iron stores may be crucial for maintaining remission.
19 citations
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June 2018 in “Breast Cancer Research and Treatment” This study found that adjuvant docetaxel treatment for breast cancer at cumulative doses of 400 mg/m² or higher is associated with a 10% prevalence of persistent alopecia leading to wig use, but this was completely prevented with scalp cooling.
1 citations
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December 2012 in “Journal of the European Academy of Dermatology and Venereology” This letter to the editor reports that sentinel lymph node status is the strongest independent predictor for both disease-free and overall survival in patients with thick melanoma.
December 2023 in “Veterinary dermatology” This study found that microneedling with longer needles (3 mm) showed better hair regrowth in dogs with hair cycle arrest, although most experienced recurrent hair loss during follow-up. Some dogs also developed minor, temporary itching.
September 2009 in “European Urology Supplements” Surgery for high-risk prostate cancer is challenging but doesn't lead to more complications, and additional treatment is often needed.
1 citations
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May 2024 in “Italian Journal of Dermatology and Venereology” This study supports the use of a national registry as an effective tool for documenting epidemiological data, disease progression, treatment responses, and quality of life impacts in patients with alopecia areata.
54 citations
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May 2019 in “Multiple Sclerosis and Related Disorders” This study found that azathioprine may improve relapses and disability in patients with neuromyelitis optica spectrum disorder but is associated with higher adverse events compared to mycophenolate mofetil.
24 citations
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February 2021 in “Dermatology and Therapy” This study reported a significant relapse in alopecia areata among patients infected with COVID-19, possibly due to the infection's inflammatory response and stress from quarantine.
16 citations
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May 2011 in “Dermatologic therapy” This article reviews side effects and relapse rates of various systemic treatments for severe alopecia areata, reporting no new clinical findings.
10 citations
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October 2018 in “Neurology Neuroimmunology & Neuroinflammation” This case report describes a 31-year-old woman experiencing alopecia areata as a potential side effect of alemtuzumab treatment for relapsing-remitting MS.
7 citations
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September 2006 in “Clinical lymphoma & myeloma” This review discusses various treatment challenges and toxicities in patients with relapsed follicular lymphoma and suggests that novel therapies could improve outcomes by reducing exposure to harmful chemotherapy cycles.
3 citations
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September 2024 in “BMC Oral Health” This study found that low-level laser therapy effectively reduced relapse rates, while functional appliances did not; combining them offered no additional benefits.
36 citations
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June 2014 in “Experimental Neurology” This review outlines the main findings from clinical trials on teriflunomide's efficacy and safety for relapsing multiple sclerosis, noting clinical considerations and exploring its mechanisms based on various studies.
31 citations
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July 1975 in “PubMed” This study reported that intensive immunosuppression in multiple sclerosis patients significantly reduced relapse rates versus pre-treatment expectations, though some required ongoing treatment after tapering.
2 citations
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September 2024 in “PLoS ONE” This study suggests that combining bendamustine with tucidinostat may improve survival in patients with relapsed or refractory adult T-cell leukemia/lymphoma, highlighting its potential for clinical investigation.
1 citations
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January 2020 in “Skin Appendage Disorders” Treatment with methotrexate and prednisolone led to complete hair regrowth and no relapse for 2 years.
1 citations
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February 2002 in “Oncology Times” This research reports that arsenic trioxide achieved a complete remission rate of 87% in patients with relapsed acute promyelocytic leukemia, though its use involves manageable toxicities.
1 citations
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May 2025 in “Indian Dermatology Online Journal” This case report links sorafenib treatment in a 22-year-old man with relapsed acute myeloid leukemia to a rare instance of drug-induced pityriasis rubra pilaris-like eruption.
January 2021 in “Journal of Cutaneous and Aesthetic Surgery” Follicular unit extraction successfully restored hair growth in a leprosy patient without disease relapse.
January 2025 in “International Journal of Medicine in Developing Countries” In this case report, a woman with relapsing-remitting multiple sclerosis on long-term Ocrelizumab developed alopecia areata years after treatment initiation, suggesting a need for further study of Ocrelizumab's long-term safety profile.
56 citations
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January 2021 in “Clinical and Experimental Medicine” This review highlights the challenges in treating alopecia areata, noting that current therapies often lead to relapse and have uncertain long-term effectiveness; it also points to potential future treatments such as JAK-STAT inhibitors and PRP.