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Hair follicles may help teach the immune system to tolerate new self-antigens, but this can sometimes cause hair loss.

Cutaneous Lymphadenoma is a unique skin tumor with specific protein markers and common gene mutations that may cause continuous cell growth.

T-cell reconstitution after thymus transplantation can cause hair whitening and loss.

New treatments targeting T-cell pathways are needed for better alopecia areata management.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.

T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Testosterone may slow down wound healing and increase inflammation.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

Red blood cell folate levels are reliable indicators of long-term folate status in alopecia areata patients.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.

Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.

Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.

Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.

Blood stem cells are diverse, influenced by many factors, and understanding them is key for progress in regenerative medicine.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.

Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.

Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.

Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.

Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.