411 citations,
May 2010 in “Gastroenterology” Targeting colon cancer stem cells might lead to better treatment results.
121 citations,
March 1989 in “Journal of Investigative Dermatology” Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.
103 citations,
November 2014 in “Journal of Cell Biology” MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
100 citations,
June 2006 in “Journal of biological chemistry/The Journal of biological chemistry” Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.
75 citations,
November 2017 in “Developmental biology” The circadian clock influences the behavior and regeneration of stem cells in the body.
56 citations,
July 2005 in “Experimental Dermatology” Injected human hair follicle cells can create new, small hair follicles in skin cultures.
53 citations,
October 2014 in “Free radical biology & medicine” Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.
47 citations,
June 2012 in “Genes & Development” A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.
31 citations,
January 2014 in “Stem Cells” Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.
24 citations,
March 2015 in “Experimental Cell Research” NFIC helps human dental stem cells grow and become tooth-like cells.
22 citations,
October 2018 in “Aesthetic Plastic Surgery” Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.
6 citations,
October 2016 in “Journal of Cellular Physiology” Human dermal fibroblasts help microvascular endothelial cells grow, but not vice versa.
6 citations,
May 2013 in “PloS one” The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
4 citations,
October 2014 in “Journal of Integrative Agriculture” Researchers found 24 genes that change significantly and affect cashmere growth in goats; this could help increase cashmere production.
4 citations,
October 2007 in “Dermatologic Clinics” Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
1 citations,
March 2023 in “PloS one” Different amounts of daylight affect cashmere growth in goats by changing the activity of certain genes and molecules.
1 citations,
January 2018 in “Elsevier eBooks” Diuretics help the body get rid of excess salt and water by acting on the kidneys in different ways.
1 citations,
January 2014 in “Elsevier eBooks” Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
1 citations,
October 1974 in “Postgraduate medicine” New drugs like clonidine and prazosin show promise for treating high blood pressure despite some side effects.
January 2024 in “Journal of cellular immunology” Hair follicle stem cells are important for maintaining healthy skin and interact with many signals.
November 2022 in “Research Square (Research Square)” The research provides insights into hair follicle growth in forest musk deer by identifying key genes and pathways involved.
138 citations,
November 2015 in “Journal of Pharmacology and Experimental Therapeutics” Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
106 citations,
December 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
71 citations,
January 2019 in “International journal of biological sciences” Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
51 citations,
September 2010 in “Trends in Endocrinology and Metabolism” Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
50 citations,
August 1999 in “Experimental dermatology” The control system for hair growth cycles is not well understood and needs more research.
47 citations,
March 2015 in “European Journal of Clinical Investigation” The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.
44 citations,
June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
21 citations,
March 2019 in “Critical Reviews in Clinical Laboratory Sciences” The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
18 citations,
January 2019 in “Expert Opinion on Biological Therapy” Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.