85 citations,
May 2019 in “Journal of neuroendocrinology” The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.
68 citations,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” HOXC13 is essential for hair and nail development by regulating Foxn1.
4 citations,
August 2022 in “Cells” lncRNA2919 slows down rabbit hair growth by stopping cell growth and causing cell death.
3 citations,
December 2023 in “Biomedicines” PRP therapy helps skin heal and improve by promoting cell growth and repair.
318 citations,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
38 citations,
January 2001 in “Neuroepidemiology” The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.
16 citations,
November 2019 in “Nanomedicine” Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.
6 citations,
October 2022 in “Frontiers in Cell and Developmental Biology” Transplanted hair follicle stem cells can heal damaged rat intestines.
62 citations,
July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
11 citations,
March 2007 in “Digestive Diseases and Sciences” The conditions alopecia areata, primary sclerosing cholangitis, and ulcerative colitis may be linked by shared autoimmune and cell death mechanisms.
1 citations,
February 2023 in “Drug Design Development and Therapy” Plant adaptogens may help treat skin diseases and improve skin health, but more research is needed to fully understand how they work.
1 citations,
January 2004 in “Hepatology” Tenofovir is more effective than adefovir for resistant hepatitis B, Fibroscan is good for assessing liver damage, regulatory T cells may help hepatitis C persist, and other insights into liver health and disease were found.
14 citations,
June 2017 in “Immunity” Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.
174 citations,
November 2016 in “Cell stem cell” Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
47 citations,
March 2019 in “Journal of immunology research” Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
39 citations,
December 2018 in “Methods in molecular biology” The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.
22 citations,
November 2007 in “Journal of Investigative Dermatology Symposium Proceedings” Hair growth and health are influenced by stress and hormones.
1 citations,
June 2017 in “Nature Reviews Immunology” Immune cells called Treg cells are essential for hair growth and regeneration.
October 2023 in “Frontiers in medicine” Targeted immunotherapy could be a promising new treatment for hair regrowth.
April 2018 in “Journal of Investigative Dermatology” Older mice healed wounds better but lost more weight and might have weaker immune systems afterward.
228 citations,
September 2012 in “Trends in Neurosciences” Nerves are crucial for the regeneration of various body parts in many animals.
147 citations,
November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
118 citations,
January 2016 in “Current Topics in Developmental Biology” The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.
64 citations,
March 2017 in “Nature communications” Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.
45 citations,
August 2019 in “Dermatologic Therapy” Hair loss treatments work better with lifestyle changes.
43 citations,
August 2018 in “Cell Stem Cell” Hoxc genes control hair growth through Wnt signaling.
39 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
37 citations,
June 2021 in “Journal of the European Academy of Dermatology and Venereology” Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.
36 citations,
March 2019 in “European Journal of Human Genetics” The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.
32 citations,
May 2012 in “PloS one” Thymic transplantation normalized some T-cells but not others, maintaining immune function.