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The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

Melatonin directly affects mouse hair follicles and may influence hair growth.

After chemotherapy for a gestational trophoblastic tumor, normal pregnancy rates are possible, but there's a slightly higher risk of the tumor reoccurring in future pregnancies.

The document summarizes medical findings on topics like heart rhythm treatment, sleep apnea therapy, and various health conditions and treatments.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

Dermal stem cells help regenerate hair follicles and heal skin wounds.

Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Lipedema is a painful fat disorder in women that's hard to treat, often worsens with hormonal changes, and requires symptom-focused therapies.

Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.

Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.

The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.

New regenerative therapies show promise for treating hair loss.

Chromosomal differences affect how muscle cells respond to testosterone.

Women with excessive hair growth tend to have shorter index and ring fingers compared to others.

Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Women may need different blood pressure guidelines than men for heart disease prevention.

Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

Breathing in high levels of certain air pollutants significantly increases women's risk of developing Polycystic Ovary Syndrome.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.

The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.