18 citations,
April 2014 in “Stem cells” The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.
7 citations,
April 2012 in “Biomolecular concepts” Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
3 citations,
January 2014 in “Elsevier eBooks” Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.
1 citations,
January 2019 in “Elsevier eBooks” New scaffold materials help heal severe skin wounds and improve skin regeneration.
October 2023 in “Biomedical science and engineering” Innovative methods are reducing animal testing and improving biomedical research.
April 2017 in “Plastic and Reconstructive Surgery – Global Open” Different levels of shear stress affect where cells move and gather in a 3D-printed model, helping to better understand cell behavior in blood vessels.
November 2014 in “Journal of Cell Biology” Valentina Greco's research shows that the environment around hair follicle stem cells is more crucial for regeneration than the stem cells themselves.
1039 citations,
February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
306 citations,
April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
218 citations,
May 2014 in “Experimental Dermatology” Skin fat cells help with skin balance, hair growth, and healing wounds.
165 citations,
October 2013 in “Nature Communications” Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.
131 citations,
March 2004 in “The American journal of pathology” Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
115 citations,
September 2012 in “Experimental Dermatology” Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.
75 citations,
October 2016 in “Genes & Development” Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
70 citations,
January 2014 in “International review of cell and molecular biology” Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
68 citations,
March 2019 in “Advanced Healthcare Materials” Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.
68 citations,
December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
67 citations,
February 2009 in “Journal of Dermatology” 49 citations,
February 2008 in “Stem Cells” Wnt10b helps blood stem cells grow after injury.
31 citations,
June 2017 in “Regeneration” BMP2 needs periosteal tissue to help regenerate mouse middle finger bones within a specific time.
29 citations,
September 2020 in “International Journal of Molecular Sciences” The document concludes that freeze-dried platelet-rich plasma shows promise for medical use but requires standardization and further research.
23 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Using defensins to activate stem cells may improve skin aging signs without causing inflammation.
19 citations,
August 2012 in “Cell death and differentiation” Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.
18 citations,
September 2020 in “International Journal of Nanomedicine” Both human and animal-derived small extracellular vesicles speed up skin healing equally well.
16 citations,
September 2016 in “Experimental Dermatology” Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.
8 citations,
January 2020 in “Biomaterials Science” Researchers developed a scaffold that releases a healing drug over time, improving wound healing and skin regeneration.
7 citations,
June 2021 in “Cell Proliferation” Low oxygen levels improve the function of hair and skin cells when they are in direct contact.
1 citations,
January 2018 in “Recent clinical techniques, results, and research in wounds” Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.
1 citations,
October 2012 in “Elsevier eBooks” Skin stem cells can help improve skin repair and regeneration.
1 citations,
February 2012 in “The American Journal of Cosmetic Surgery” UBM helps hair regrowth in men and women with hair loss.