25 citations,
January 2015 in “World journal of stem cells” Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.
13 citations,
October 2002 in “Journal of Investigative Dermatology” The upper half of a human hair follicle can grow a new hair in a mouse, but success is rare.
12 citations,
June 2018 in “Journal of Cosmetic Dermatology” PRP is effective for hair loss and might work better with other treatments, but more research is needed.
Low-level laser therapy may help stem cells grow and function better, aiding in healing and tissue repair.
188 citations,
March 2018 in “Frontiers in Immunology” Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.
84 citations,
December 2017 in “EMBO Reports” Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.
36 citations,
April 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Canine hair follicles have stem cells similar to human hair follicles, useful for studying hair disorders.
18 citations,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
4 citations,
January 2022 in “Transfusion Medicine and Hemotherapy” Platelet-Rich Plasma (PRP) has potential benefits in plastic surgery, especially for skin grafts, wound healing, hair loss, mild Carpal Tunnel Syndrome, and TMJ disorders, but more research is needed to confirm its effectiveness.
4 citations,
September 2020 in “Cell division” XMU-MP-1 stops cell growth in a human mini-organ and reduces the effectiveness of the chemotherapy drug paclitaxel.
3 citations,
June 2017 in “Journal of Biomaterials Applications” Keratin extract from human hair was found to promote hair growth in mice.
2 citations,
December 2022 in “Journal of Biochemistry and Molecular Biology” Organoids created from stem cells are used to model diseases, test drugs, and develop personalized and regenerative medicine.
1 citations,
October 2023 in “European journal of histochemistry” Ozone and procaine boost the release of healing factors in platelet-rich plasma.
September 2017 in “Current stem cell research & therapy” Mesenchymal stem cells from fat tissue may effectively treat hair loss and help regrow hair.
320 citations,
December 2018 in “Frontiers in Immunology” Changing how mesenchymal stromal cells are grown can improve their healing abilities.
305 citations,
March 2018 in “International journal of molecular sciences” The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.
222 citations,
October 2014 in “Annual Review of Pharmacology and Toxicology” Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.
132 citations,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
46 citations,
June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
42 citations,
May 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
35 citations,
April 2008 in “Human Molecular Genetics” Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
26 citations,
July 2016 in “PLOS ONE” Activating β-catenin in certain skin cells speeds up hair growth in mice.
23 citations,
January 2020 in “Central-European Journal of Immunology/Central European Journal of Immunology” Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.
20 citations,
September 2020 in “Journal of Translational Medicine” Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.
19 citations,
January 2017 in “Stem Cells International” Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.
6 citations,
September 2015 in “Journal of Investigative Dermatology” Using special RNA to target a mutant gene fixed hair problems in mice.
6 citations,
January 2011 in “Springer eBooks” Nutrition is important for skin health, and changing diet can help prevent and treat skin diseases.
5 citations,
January 2017 in “Molecular Medicine Reports” Human hair follicle cells can be turned into neural stem cell-like cells, which might help treat brain diseases.
January 2024 in “Burns and trauma” The skin microbiome helps heal wounds and can be targeted to improve healing.
January 2023 in “Annali di stomatologia” PRP helps heal and repair tissues in medicine but needs more research for better use.