research Stem Cell Therapy and Hair Loss: Present Evidence and Future Perspectives
Stem cell therapy shows promise for hair loss treatment, but more research is needed to confirm its effectiveness.
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research Telomere Dynamics and Telomerase in the Biology of Hair Follicles and Their Stem Cells as a Model for Aging Research
Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
research Editorial: Hair Follicle Stem Cell Regeneration in Aging
Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.
research Autophagy Critically Controls Skin Inflammation and Apoptosis-Induced Stem Cell Activation
Autophagy helps control skin inflammation and cancer responses and regulates hair growth by affecting stem cell activity.
research A Desmosomal Cadherin Controls Multipotent Hair Follicle Stem Cell Quiescence and Orchestrates Regeneration Through Adhesion Signaling
A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.
research Application of Mesenchymal Stem Cells for Anti-Senescence and Clinical Challenges
Mesenchymal stem cells could help treat aging-related diseases better than current methods.
research Pathology of Mouse Models of Accelerated Aging
Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
research Phospholipase A2 in Skin Biology: New Insights from Gene-Manipulated Mice and Lipidomics
Phospholipase A2 enzymes play key roles in skin health and disease.
research Hair Shaft Miniaturization Causes Stem Cell Depletion Through Mechanosensory Signals Mediated by a Piezo1-Calcium-TNF-α Axis
Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.
research Follistatin Promotes LIN28B-Mediated Supporting Cell Reprogramming and Hair Cell Regeneration in the Murine Cochlea
Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.
research Transdifferentiation of Human Hair Follicle Mesenchymal Stem Cells into Red Blood Cells by OCT4
Human hair follicle stem cells can be turned into red blood cells.
research Dysregulated Behavior of Hair Follicle Stem Cells Triggers Alopecia and Provides Potential Therapeutic Targets
Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.
research Enhancement of Hair Growth Through Stimulation of Hair Follicle Stem Cells by Prostaglandin E2 Collagen Matrix
Prostaglandin E2 collagen matrix may help stimulate hair growth.
research Advances in Hair Growth
The best long-lasting results in treating hair loss may be achieved through combination therapy, including treatments like finasteride, minoxidil, and platelet-rich plasma injections.
research Harnessing Mesenchymal Aggregation for Engineered Organ-Level Regeneration: Recent Progress and Perspective
Scientists are using clumps of special stem cells to improve organ repair.
research Novel Path Breaking Vistas in Dentistry
Recent dental research shows diet changes increased tooth decay, red wine reduces bacteria, and dental stem cells can regenerate dentin.
research Faculty Opinions Recommendation of FGF9 from Dermal γδ T Cells Induces Hair Follicle Neogenesis After Wounding
A substance called FGF9 from certain immune cells can trigger new hair growth during wound healing in mice, but humans may not have the same response due to fewer of these cells.
research Faculty Opinions Recommendation of FGF9 from Dermal γδ T Cells Induces Hair Follicle Neogenesis After Wounding
FGF9 from certain cells can trigger new hair growth during wound healing, but humans have fewer of these cells, which may limit hair regrowth.
research Hairy Tale of Signaling in Hair Follicle Development and Cycling
Hair growth and development are controlled by specific signaling pathways.
research Fibroblast Growth Factors: Key Players in Regeneration and Tissue Repair
Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
research Epidermal Wnt/β-Catenin Signaling Regulates Adipocyte Differentiation via Secretion of Adipogenic Factors
Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.
research Cell Fate Decisions: Emerging Roles for Metabolic Signals and Cell Morphology
Metabolic signals and cell shape influence how cells develop and change.
research A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock
BMAL1 and Period1 genes can influence human hair growth.
research Lysophospholipid Mediators in Health and Disease
Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
research Neuregulin3 Alters Cell Fate in the Epidermis and Mammary Gland
Neuregulin3 affects cell development in the skin and mammary glands.
research A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research Platelet-Derived Bio-Products: Classification Update, Applications, Concerns, and New Perspectives
Platelet-derived bio-products help in wound healing and tissue regeneration but lack standardized methods, and their use in medicine is growing.
research The Parathyroid Hormone Second Receptor PTH2R and its Ligand Tuberoinfundibular Peptide of 39 Residues TIP39 Regulate Intracellular Calcium and Influence Keratinocyte Differentiation
The study investigated the role of the parathyroid hormone second receptor (PTH2R) and its ligand, tuberoinfundibular peptide of 39 residues (TIP39), in skin biology, focusing on keratinocyte differentiation and calcium homeostasis. TIP39 and PTH2R were found in human and mouse skin, with TIP39 increasing intracellular calcium levels in keratinocytes, promoting differentiation. This was evidenced by decreased keratin-14 and increased involucrin expression. PTH2R−/− mice showed increased epidermal thickness, suggesting TIP39 and PTH2R's role in regulating keratinocyte function and skin development. The study highlighted TIP39's potential impact on calcium transport and genetic skin disorders, emphasizing the need for further research on PTH-related genes in skin function.
research PTEN Mediates Activation of Core Clock Protein BMAL1 and Accumulation of Epidermal Stem Cells
PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.
research When The Circadian Clock Meets The Melanin Pigmentary System
Silencing certain circadian clock genes increases skin pigmentation.