65 citations,
April 2020 in “International Journal of Molecular Sciences” PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.
50 citations,
March 2014 in “Stem Cells” Stem cell niches are adaptable and key for tissue maintenance and repair.
43 citations,
January 2011 in “Plastic and Reconstructive Surgery” Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.
4 citations,
January 2013 in “Advances in Experimental Medicine and Biology” Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
1 citations,
January 2017 in “Elsevier eBooks” The document concludes that new treatments for hair loss may involve a combination of cosmetics, clinical methods, and genetic approaches.
66 citations,
May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
13 citations,
March 2012 in “The Journal of Dermatology” Hair transplant surgery can rebuild muscle and nerve connections, allowing transplanted hairs to stand up like normal hairs.
10 citations,
July 2011 in “Wound Repair and Regeneration” New antiscarring strategies show promise, including drugs, stem cells, and improved surgical techniques.
December 2023 in “Regenerative Therapy” Stem cell and platelet-rich plasma therapies show promise for COVID-19 related hair loss, but more research is needed.
8 citations,
January 2015 in “Journal of Cutaneous Medicine and Surgery” Hair restoration techniques have improved but still rely on limited donor hair, with new methods like cloning and gene therapy being explored.
June 2018 in “Advances in Cosmetic Surgery” Hair loss caused by genetics and hormones; more research needed for treatments.
May 2018 in “Journal of Investigative Dermatology” DPP4 is important for scarring and skin regeneration, and managing its activity could improve skin healing treatments.
333 citations,
February 2010 in “Cell Stem Cell” Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
110 citations,
August 2017 in “Immunology” Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
48 citations,
March 2019 in “Frontiers in Physiology” Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.
43 citations,
July 2016 in “Clinics in Plastic Surgery” The conclusion is that fat grafting is safe and effective but carries risks that need careful management.
25 citations,
January 2015 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
1 citations,
June 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” The symposium highlighted the importance of understanding disease mechanisms for targeted dermatology treatments.
26 citations,
March 2017 in “Pharmacology & Therapeutics” New drugs for heart disease may be developed from molecules secreted by stem cells.
7 citations,
February 2018 in “InTech eBooks” Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.
A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.
178 citations,
February 2018 in “Advances in wound care” New effective scar treatments are urgently needed due to the current options' limited success.
85 citations,
October 2015 in “Proceedings of the National Academy of Sciences of the United States of America” NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.
83 citations,
May 2013 in “International Journal of Molecular Sciences” Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
2 citations,
December 2022 in “Journal of Biochemistry and Molecular Biology” Organoids created from stem cells are used to model diseases, test drugs, and develop personalized and regenerative medicine.
92 citations,
August 2017 in “Proceedings of the National Academy of Sciences of the United States of America” Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.
84 citations,
December 2017 in “EMBO Reports” Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.
23 citations,
December 2020 in “Frontiers in Cell and Developmental Biology” Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.
21 citations,
November 2017 in “Journal of Investigative Dermatology” The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.
14 citations,
October 2018 in “Brain Research Bulletin” Exosomes help nerve fibers grow by affecting specific cell signaling pathways.