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High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

The research found ways to activate melanocyte stem cells for potential treatment of skin depigmentation conditions.

New tissue engineering strategies show promise for regenerating human hair follicles, which could improve hair loss treatments.

A specific molecular switch, driven by MAPK/ERK signaling, helps spiny mice heal wounds by regenerating skin instead of forming scars.

The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.

Hair follicles can regenerate if cut at certain points, with stem cells in the upper part.

Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.

Most vertebrates can regenerate skin, nails, and corneas, but only some can regenerate teeth and lenses.

Epithelial stem cells can adapt and help in tissue repair and regeneration.

African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

Keratin from human hair helps nerves heal faster.

Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Nerves are crucial for the regeneration of various body parts in many animals.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.

Wnt ligands are crucial for hair growth and repair.

Telocytes might help with skin repair and regeneration.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

A wearable device using electric stimulation can significantly improve hair growth.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

New methods for skin and nerve regeneration can improve healing and feeling after burns.

The DNA hydrogel helps heal diabetic wounds by absorbing fluids, warming, sticking to tissue, killing bacteria, and aiding tissue and hair regrowth.