22 citations,
May 2011 in “European Journal of Cancer” In this phase I study, 25 patients with advanced solid tumors were treated with a combination of SU-014813, an oral multi-targeted tyrosine kinase inhibitor, and docetaxel. The study aimed to determine the maximal tolerated dose, evaluate pharmacokinetics, and assess preliminary anti-tumor efficacy. The recommended phase II dose was established as docetaxel 75 mg/m² with SU-014813 50 mg/day. Dose-limiting toxicities included neutropenia, neutropenic fever, fatigue, and diarrhea, while other side effects were fatigue, alopecia, nausea, vomiting, anorexia, rash, hypertension, and hair discoloration. Two patients (8%) achieved partial response, and 7 patients (29%) had disease stabilization for over 6 months, resulting in a clinical benefit rate of 37.5%. The regimen showed particular promise in patients with melanoma and sunitinib-refractory gastrointestinal stromal tumors, warranting further development.
11 citations,
November 2019 in “Clinical Case Reports” A Brazilian teenager with severe hair loss had total hair regrowth with no side effects after using tofacitinib.
3 citations,
December 2000 in “Journal of the Royal Society of Medicine” Antiandrogen therapy may be beneficial for women with hidradenitis suppurativa.
1 citations,
June 2022 in “PubMed” Alopecia causes hair loss and should be treated early, especially scarring types where hair cannot regrow.
June 2023 in “Brazilian Journal of Health Review” Common baldness is a hereditary condition that can be treated with medications or surgery to prevent progression and improve self-esteem.
January 2015 in “Indian Dermatology Online Journal” The patient's hair loss is most likely due to diffuse alopecia areata.
March 2005 in “Journal of The American Academy of Dermatology” Metabolic syndrome can cause serious health issues and should be considered when treating women with severe acne.
20 citations,
February 2001 in “Dermatologic Surgery” Micropigmentation effectively hides scalp scars with few complications.
5 citations,
January 2006 in “Journal of obstetrics and gynaecology” Metformin can cause hair loss in some women with PCOS.
1 citations,
March 2020 in “QJM: An International Journal of Medicine” Lactoferrin levels are lower in people with chronic hair shedding, suggesting supplements could help treat it.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Some African American women experience central scalp hair loss, often linked to a history of fungal scalp infection.
80 citations,
September 1984 in “Journal of The American Academy of Dermatology” 5% minoxidil helps hair regrowth in androgenic alopecia.
67 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.
50 citations,
September 1975 in “American Heart Journal” Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.
46 citations,
April 1977 in “Southern Medical Journal” Minoxidil causes excessive hair growth, but depilatory agent removes it safely and effectively.
44 citations,
April 2015 in “Journal of the American Academy of Dermatology” Combining diphenylcyclopropenone with anthralin is more effective for hair regrowth in alopecia areata than using diphenylcyclopropenone alone, but may cause more side effects.
33 citations,
January 2018 in “The International Journal of Developmental Biology” Cell aging can be both good and bad for tissue repair.
30 citations,
February 2017 in “Histochemistry and Cell Biology” TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.
23 citations,
December 2004 in “Seminars in oncology” Liposomal anthracyclines are effective and safer for treating multiple myeloma, especially in elderly patients.
21 citations,
March 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Telogen is an active phase with important biological processes, not a resting phase.
19 citations,
July 1983 in “American Journal of Kidney Diseases” Minoxidil lowers blood pressure in kids with kidney issues, but use carefully due to side effects.
13 citations,
July 2010 in “Journal of The American Academy of Dermatology” A man with Cronkhite-Canada syndrome had all 20 nails detach but improved with treatment.
12 citations,
March 2018 in “Australasian Journal of Dermatology” Minoxidil treatment can reduce hair shedding, increase hair volume, and even change hair color in patients with loose anagen hair syndrome.
11 citations,
April 2009 in “Pharmacotherapy” Minoxidil can cause deadly skin reaction; monitor patients closely.
9 citations,
April 2015 in “Dermatologic Therapy” Hormonal therapies, like flutamide and cyproterone acetate, are safe and effective for treating adult women's acne, especially those with hormone imbalance or resistant acne.
9 citations,
November 2013 in “Dermatologic Surgery” Hair transplant complications were likely due to deep graft placement and rough handling.
7 citations,
September 2013 in “Current Dermatology Reports” Some skin medications are safe for pregnant women, but others pose risks or should not be used.
6 citations,
September 1988 in “Drug intelligence & clinical pharmacy” Minoxidil caused a severe rash in a patient, which improved after stopping the drug.
5 citations,
March 2021 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil is an effective and safe treatment for hair loss.
3 citations,
June 2022 in “Dermatology and therapy” A new botanical treatment improved hair growth and symptoms in lichen planopilaris patients.