research Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors
The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.
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research BAYONET Trial: Staged Combination With Encorafenib, Binimetinib, Plus Cetuximab Following Encorafenib Plus Cetuximab for BRAF V600E-Mutant Metastatic Colorectal Cancer
The combination treatment showed a higher response rate but no significant survival benefits.
research Side Effects of Vitamins, Amino Acids, Nutrition, and Complementary and Alternative Medicine
Some vitamins, amino acids, and alternative medicines can cause serious side effects, including bone, muscle, and skin issues, and healthcare professionals should be aware of these risks.
research Laser Hair Removal in Alopecia Areata of the Scalp: A Novel Therapeutic Approach
Laser hair removal can be an effective last-resort treatment for men with stubborn Alopecia Areata who want to be uniformly bald.
research Signal Transducer and Activator of Transcription 5B Deficiency Due to a Novel Missense Mutation in the Coiled-Coil Domain
A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.
research Baricitinib-Loaded EVs Promote Alopecia Areata Mouse Hair Regrowth by Reducing JAK-STAT-Mediated Inflammation and Promoting Hair Follicle Regeneration
Baricitinib-loaded EVs help hair regrowth in alopecia areata by reducing inflammation and promoting hair follicle regeneration.
research Micropigmentation as an Adjuvant in Cosmetic Surgery of the Scalp
Micropigmentation effectively hides scalp scars with few complications.
research Redefining Hormone Resistance in Prostate Cancer
The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
research Central Hair Loss in African American Women: Incidence and Potential Risk Factors
Some African American women experience central scalp hair loss, often linked to a history of fungal scalp infection.
research Mycophenolate Mofetil as an Alternative Treatment for Autoimmune Hepatitis
Mycophenolate mofetil can effectively treat autoimmune hepatitis when standard drugs fail.
research Characteristics and Outcomes of Patients on Tofacitinib for Alopecia Areata or Rheumatoid Arthritis: A Retrospective Cohort Study
Patients with rheumatoid arthritis using tofacitinib had more serious side effects than those with alopecia areata.
research Clinical Utility of GnRH Analogues in Female Androgen Excess: Highlighting Diagnostic and Therapeutic Applications
GnRH analogues are effective for diagnosing and treating female androgen excess, offering a non-surgical option.
research Studying Cytotoxic T-Lymphocyte-Associated Antigen-4 (CTLA-4) Gene Polymorphism in a Sample of Iraqi Women with Polycystic Ovarian Syndrome
The CTLA-4 gene change studied does not affect Polycystic Ovarian Syndrome in the women tested.
research A Case of Folliculitis Decalvans With Concomitant Acne Keloidalis Nuchae, Androgenic Alopecia, and Profound Postinflammatory Hyperpigmentation
Folliculitis decalvans mainly affects middle-aged African American men and is treated with antibiotics.
research A Case Report of Cronkhite-Canada Syndrome Complicated by Membranous Nephropathy
Rituximab may be an effective treatment for Cronkhite-Canada syndrome with kidney disease.
research High-Potency Topical Steroids: An Effective Therapy for Chronic Scalp Inflammation in Rapp-Hodgkin Ectodermal Dysplasia
Strong skin creams work well for long-term scalp inflammation in Rapp-Hodgkin Ectodermal Dysplasia.
research Exploiting the Origins of Ras-Mediated Squamous Cell Carcinoma to Develop Novel Therapeutic Interventions
Researchers found that hair follicle stem cells can become squamous cell carcinoma due to Ras activation, which could lead to new treatments.
research Safety of Common Medications for Treating Dermatology Disorders in Pregnant Women
Some skin medications are safe for pregnant women, but others pose risks or should not be used.
research Scalp Micropigmentation: A Concealer for Hair and Scalp Deformities
Scalp micropigmentation, a cosmetic tattoo technique, is a promising non-surgical treatment for hair and scalp deformities, despite potential complications.
research Alopecia Universalis Associated With Hyperthyroidism Treated With Azathioprine And Hydroxychloroquine: A Case Report
A woman with complete hair loss and severe hyperthyroidism was successfully treated with azathioprine and hydroxychloroquine.
research Fatal Toxic Epidermal Necrolysis Associated With Minoxidil
Minoxidil can cause deadly skin reaction; monitor patients closely.
research Vitamin A Toxicity: When One a Day Doesn't Keep the Doctor Away
Vitamin A toxicity can cause severe health issues and may require a liver transplant if other treatments fail.
research Macroenvironmental Regulation of Hair Cycling and Collective Regenerative Behavior
Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
research Role of Liposomal Anthracyclines in the Treatment of Multiple Myeloma
Liposomal anthracyclines are effective and safer for treating multiple myeloma, especially in elderly patients.
research Finasteride for the Treatment of Hidradenitis Suppurativa in Children and Adolescents
Finasteride reduces Hidradenitis Suppurativa flare-ups in children and teens, but long-term safety is unknown.
research Psychodermatology in the UK: Psychological Impact and Integrated Treatments
Treating skin conditions with both psychological and dermatological care improves patient outcomes and can save costs.
research Pityrosporum Folliculitis in Immunocompromised Populations: A Systematic Review
Treating underlying conditions and using antifungals effectively resolve Pityrosporum folliculitis in immunocompromised people.
research Endocrine Disorders and Hormonal Therapy for Adolescent Acne
Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.
research Case 2-2022: An Adolescent Male in Cardiac Arrest 3 Days After Liver Transplantation for End-Stage Liver Disease
The patient recovered well and returned to college without any lasting issues.
research The Usual Treatment of Trigeminal Autonomic Cephalalgias
The document concludes that inhalation of oxygen and sumatriptan injections are primary for cluster headaches, indomethacin for paroxysmal hemicrania, and lidocaine and lamotrigine for SUNCT, but SUNCT often resists treatment.