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This review discusses multisystem inflammatory syndrome in adults (MIS-A) related to SARS-CoV2 and outlines the existing knowledge and unanswered questions, reporting no new clinical results.

In this systematic review, researchers reported that various types of laser therapy effectively treat hidradenitis suppurativa at different severity stages, with each laser offering specific benefits such as lesion removal, inflammation reduction, and improved quality of life.

In this narrative hypothesis-driven overview, the authors propose reframing rosacea as a neuroimmune disorder, highlighting the interconnected role of the skin-gut-brain axis, particularly central nervous system involvement alongside gut microbiota and neurogenic inflammation, to emphasize the need for multidisciplinary therapeutic approaches.

This review discusses the repurposing of auranofin for oncological and non-oncological uses and highlights its early-stage clinical trial findings, suggesting further exploration of its therapeutic potential.

In this review, platelet concentrates were found to show comparable efficacy to steroids and immunosuppressive drugs in treating oral lichen planus, with some studies reporting more benefits and others noting more severe adverse reactions with platelet treatments.

This review outlines the functional anatomy, pathology, and molecular mechanisms of androgenetic alopecia, emphasizing the need for multi-omics approaches to better understand this condition's biology.

In this case report, a four-year-old girl was diagnosed with vitamin D-dependent rickets type II, manifesting as diffuse alopecia, frontal bossing, hypoplastic teeth, and skin-colored papules, due to a genetic mutation causing resistance to 1.25-dihydroxy vitamin D.

This systematic review suggests that platelet-rich plasma may significantly improve symptoms in oral lichen planus with effects comparable to corticosteroids, although more research is needed to confirm these findings.

Combining PRP with microneedling and minoxidil may help treat severe hair loss.

This review discusses treatments for demodicosis in adults and children and provides no new clinical results; the authors emphasize the need for careful diagnosis and therapy selection.

This review discusses the composition, preparation, and applications of autologous platelet and extracellular vesicle-rich plasma, highlighting its potential benefits and the need for further research, but it reports no new clinical findings.

This scoping review identifies various pharmacological agents and five key mechanistic strategies being studied in vivo to mitigate multi-organ toxicity caused by cytarabine, with apraglutide and N-acetylcysteine highlighted as promising candidates for clinical application.

This review details the prevalence and management of ejaculatory disorders in men with benign prostatic hyperplasia-related urinary symptoms and highlights the importance of preserving peri-montanal tissue during treatment to maintain antegrade ejaculation.

This review discusses metal-organic frameworks for treating diabetic infected wounds and related applications, reporting no new clinical results but highlighting challenges like biosafety and production for future research.

In this systematic review, animal studies showed that cytarabine causes multi-organ toxicities, notably neurotoxicity, linked to oxidative stress and other mechanisms, though study quality raises concerns about reliability and translation to human outcomes.

This review highlights the significant impact of cutaneous and oral mucosal adverse events on patients undergoing breast cancer treatment, emphasizing the need for early detection and comprehensive management to maintain treatment adherence and enhance patient care.

In this phase 3 trial analysis, baricitinib improved scalp hair growth in adults with severe alopecia areata, with a faster and higher response in those receiving 4 mg compared to 2 mg, but response varied with severity at baseline and continued through week 52.

This review explores the potential impact of nutrition on immune-mediated inflammatory skin diseases and evaluates whether dietary changes could help in treatment planning, but it presents no new clinical outcomes.

This study discusses how emerging biologics and small molecule therapies could enhance disease management and pediatric health outcomes for chronic skin conditions, suggesting their potential inclusion in treatment guidelines pending ongoing clinical trial successes.

This review examines experimental studies on the synergistic use of platelet-rich plasma and adipose-derived mesenchymal stem cells for wound healing in animal models, without reporting new clinical outcomes.

This case report from Tishreen Hospital describes the rare presentation of lupus erythematosus tumidus and autoimmune thyroid dysfunction as initial manifestations of systemic lupus erythematosus, highlighting the importance of early diagnosis for better outcomes.

This review found that vesicle-based therapies, including mammalian MSC-derived and plant-derived vesicles, consistently promote wound healing in preclinical models of thermal injury and may offer a safer alternative to live cell transplants.

This review discusses the use of adipose tissue and platelet-rich plasma in tissue repair and regeneration, noting their promise in surgical outcomes but emphasizing the need for further research to optimize therapies.

This study reviewed existing research on the use of cannabinoids for hair, scalp, and skin conditions, finding moderate evidence for their efficacy in conditions like atopic dermatitis and psoriasis, but noted limited evidence and no standardized guidelines for treatment.

In this case series, low-dose oral metformin was associated with improvements in symptoms and gene expression changes in Black female patients with treatment-resistant central centrifugal cicatricial alopecia, suggesting a potential therapeutic role for metformin in managing this condition.

This study reported that seminal vesiculoscopy combined with transurethral resection of ejaculatory ducts and balloon dilation effectively resolved hematospermia and improved symptoms in a patient whose condition was unresponsive to medical treatments.

This study investigated using baricitinib-loaded mesenchymal stem cell exosomes injected locally in an alopecia areata mouse model and found that this method improved hair regrowth better than baricitinib or exosomes alone, potentially offering a new therapeutic approach for treating alopecia areata.

This source reports that the approval of baricitinib and ritlecitinib, which are JAK inhibitors, has marked a significant advancement in treating severe alopecia areata (AA), and suggests that additional treatments with new mechanisms may further improve patient outcomes in the future.

In this study, both fractional carbon dioxide laser therapy and cryotherapy were found to be effective and safe for treating patchy alopecia areata, showing similar efficacy in improving hair growth compared to untreated control patches.

This study suggests that allogenic human mesenchymal stem cell treatments have potential therapeutic effects by inducing immune tolerance and anti-inflammatory effects in severe alopecia areata patients.