January 2023 in “Åbo Akademi University Research Portal” This study found that vimentin is essential for proper wound healing and cell growth by influencing EMT signaling and mTOR activity in mice.
November 2022 in “LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)” Platelet-rich fibrin speeds up burn wound healing in rabbits.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study applied a new RGB trichrome stain to human skin samples, revealing distinct structural staining in normal tissues and potential proteoglycan-rich zones in hair follicles.
June 2022 in “Al-Qadisiyah Journal of Veterinary Medicine Sciences” This study found that 660 nm laser treatment and povidone iodine both eradicated Pseudomonas aeruginosa infection in mice wounds, with the laser enhancing healing, and the combination provided additive or synergistic healing benefits.
This study identified a genetic locus associated with rhabdomyosarcoma susceptibility in mice and found that specific differentiation markers are linked to the regression of basal cell carcinoma.
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers found that in growing skin tissue, epidermal wound healing occurs at the expense of normal skin development, as it impairs hair follicle growth and does not activate tissue morphogenesis genes.
January 2019 in “Springer eBooks” Platelet-rich plasma therapy may have benefits and is generally safe, but more research is needed to confirm its effectiveness and safety.
January 2019 in “Advances in stem cells and their niches” This review outlines the various fibroblast subsets in the skin dermis, their origins, and their influence on epidermal stem cell behavior, highlighting the role of the local dermal niche in stem cell plasticity.
January 2019 in “Springer eBooks” Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.
April 2018 in “Journal of Investigative Dermatology” In this animal study, the researchers found that DPP4 plays a crucial role in scar formation and wound-induced hair follicle neogenesis in mice, impacting regenerative repair.
April 2018 in “Journal of Investigative Dermatology” This study found that the protein p63 requires morphogenetic signals to regulate gene expression effectively during skin cell differentiation, highlighting its complex role in therapeutic reprogramming for conditions like epidermolysis bullosa.
May 2017 in “InTech eBooks” This review outlines various complications associated with hair transplantation, noting that while most are mild and manageable, serious complications like necrosis can occur if proper care is not taken.
January 2016 in “Research Explorer (The University of Manchester)” Activating the Eda/Edar pathway improves wound healing by enhancing hair follicle growth.
Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.
November 2013 in “Elsevier eBooks” This review discusses the evolving understanding of epithelial stem cells, noting how new models challenge old assumptions and suggesting multiple stem cell populations contribute differently to skin and hair follicle regeneration.
This historical review discusses the ancient Egyptians' advanced wound-healing techniques, including the use of honey and moldy bread, and reports no new clinical results.
January 2012 in “Elsevier eBooks” This chapter reviews therapies for skin and corneal regeneration and hair loss, discussing various treatments but presenting no new research findings.
February 2009 in “Journal of The American Academy of Dermatology” Fractional infrared technology is effective and safe for treating cervical laxity.
February 2009 in “Journal of The American Academy of Dermatology” This pilot study found that fractional infrared technology improved skin laxity and thickness in the cervical area of four female patients without causing adverse effects.
February 2009 in “Journal of The American Academy of Dermatology” This study found that fractional infrared technology may improve skin laxity and thickness in the cervical area without side effects in a small group of patients.
February 2009 in “Journal of The American Academy of Dermatology” This study suggests that fractional infrared technology may effectively improve cervical skin laxity by enhancing dermal thickness without adverse effects in a small pilot group.
November 2008 in “Medical & surgical dermatology” This study reports that a prototype device may accurately measure changes in hair quantity, diameter, and density in patients with balding by assessing the cross-sectional area of hair bundles.
June 2008 in “Dermatologic Surgery” This review discusses the effects of hydrogen peroxide in hair restoration surgery and other medical specialties, finding both potential benefits and risks, but reports no conclusive data for its optimal use in hair transplants.
This dissertation reported that the loss of Ovol2 impairs hair follicle regeneration and wound repair in mice, highlighting its role in regulating directional migration of epithelial cells.
January 2012 in “Vitamins & trace elements” This study observed that smokers and alcohol consumers with androgenetic alopecia had significantly lower serum levels of antioxidant vitamins, and these habits may trigger earlier onset of alopecia in susceptible individuals.
This study found that αvβ6 integrin inhibits keratinocyte proliferation during wound healing and hair regeneration, suggesting its downregulation may enhance recovery and influence epidermal stem cell behavior.
May 2026 in “Signal Transduction and Targeted Therapy” This study found that rete ridge morphogenesis in mammalian skin is directed by a BMP-dependent developmental program, which is evolutionarily distinct from other known pathways controlling the development of hair follicles, sweat glands, and fingerprint ridges.
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February 2007 in “Cell” This article reviews the biology of epithelial stem cells and their role in tissue self-renewal, maintenance, and regeneration, and it highlights the clinical implications of understanding their signaling pathways, but it presents no new clinical findings.
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November 2013 in “Nature” This study found that differentiated airway epithelial cells can revert into functional stem cells in vivo, suggesting a more general role for this dedifferentiation process in tissue regeneration in higher vertebrates.
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October 2012 in “Journal of Morphology” This study identified the distribution of keratin-associated proteins during cornification in the epidermis of reptiles, revealing unique structural characteristics in sauropsid keratin proteins compared to other vertebrates.