research Determination of Finasteride in Tablets by High Performance Liquid Chromatography
Found accurate way to measure finasteride in tablets.
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research Application of Different Analytical Techniques and Microbiological Assays for the Analysis of Macrolide Antibiotics from Pharmaceutical Dosage Forms and Biological Matrices
Future work on macrolide antibiotic analysis will aim to enhance selectivity, sensitivity, and efficiency using advanced chromatographic methods.
research Preventive Effects of Monascus on Androgen-Related Diseases: Androgenetic Alopecia, Benign Prostatic Hyperplasia, and Prostate Cancer
Monascus helps prevent baldness, prostate issues, and may be a natural alternative to medications.
research Pantolactams as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production
Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
research The Identification of Molecular Mechanisms from Bioactive Compounds in Sansevieria Trifasciata Plant as Anti-Alopecia: In-Silico Approach
Compounds from the Sansevieria trifasciata plant might be effective for treating hair loss.
research Drug Delivery Systems Based on Microneedles for Dermatological Diseases and Aesthetic Enhancement
Microneedle patches improve drug delivery for skin treatments and cosmetic enhancements.
research Evaluation of Retardant Property of Green Hair Growth Retardant Formula
The green cream safely slowed hair growth by 25%.
research An Efficient Synthesis of Dutasteride: Utilizing Benzoyl Group as Novel Lactamic Protecting Group
Researchers created a new, efficient way to make Dutasteride, a hair loss and prostate drug, with high purity using a benzoyl group.
research Isolation and Structural Characterization of Degradation Products of Finasteride by Preparative HPLC, HRMS, and 2D NMR
Finasteride forms three new products under acidic stress.
research The ZIP7 Gene (Slc39a7) Encodes a Zinc Transporter Involved in Zinc Homeostasis of the Golgi Apparatus
The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.
research 2-Substituted 4-(Thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
research The Proximal Promoter of the Human Transglutaminase 3 Gene
The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.
research Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide
Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
research A New Catalyst for Organic Synthesis: Mercuric Triflate
Mercuric triflate is an effective catalyst for various organic reactions, working well at room temperature with high yields.
research Evidence That the Satin Hair Mutant Gene Foxq1 Is Among Multiple and Functionally Diverse Regulatory Targets for Hoxc13 During Hair Follicle Differentiation
The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.
research Suppression of Fibroblast Proliferation and Lysyl Hydroxylase Activity by Minoxidil
Minoxidil slows fibroblast growth and collagen production, potentially treating keloids, hypertrophic scars, and connective tissue disorders.
research A Keratinocyte-Specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid
CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.
research Review of Fluconazole Properties and Analytical Methods for Its Determination
Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.
research Interactions of the Vitamin D Receptor with the Corepressor Hairless
Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.
research Normal Fur Development and Sebum Production Depend on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands
FA2H is essential for normal fur and sebum production in mice.
research Computational Design and Development of a Novel Voltammetric Sensor for Minoxidil Detection Based on Electropolymerized Molecularly Imprinted Polymer
New sensor detects minoxidil accurately and effectively.
research GLI2-Specific Transcriptional Activation of the Bone Morphogenetic Protein/Activin Antagonist Follistatin in Human Epidermal Cells
GLI2 increases follistatin production in human skin cells.
research Synthesis and Characterization of Inclusion Complex of the Vasodilator Drug Minoxidil with β-Cyclodextrin
Minoxidil mixed with β-cyclodextrin improves solubility and gradual release.
research In Vivo Hair Growth-Promoting Efficacies of Herbal Extracts and Their Cubosomal Suspensions
Some herbal extracts, especially when used in cubosomal suspensions, were as effective as Minoxidil in promoting hair growth.
research Stimulatory Effect of Brazilian Propolis on Hair Growth Through Proliferation of Keratinocytes in Mice
Brazilian propolis was found to speed up hair growth in mice by increasing the growth of skin cells that form hair.
research Chapter 17: Selective Androgen Receptor Modulators (SARMs)
Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.
research New Biomarkers to Evaluate Hyperandrogenemic Women and Hypogonadal Men
The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
research Physicochemical Characterization of Finasteride: PEG 6000 and Finasteride: Kollidon K25 Solid Dispersions, and Finasteride: Beta-Cyclodextrin Inclusion Complexes
Finasteride's solubility and bioavailability improved by forming solid dispersions and inclusion complexes.
research Hair Growth Promoting Effect of Dicerocaryum Senecioides Phytochemicals
Chemicals from the plant Dicerocaryum senecioides were found to safely speed up and increase hair growth in mice.
research Dual Inhibitors of Urease and Carbonic Anhydrase-II from Iris Species
Some natural compounds from Iris plants can block enzymes related to certain disorders, with a few affecting both targeted enzymes.