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    Research 661–690 of 1000+

    1. PNU 157706, a novel dual type I and II5α-reductase inhibitor The Journal of Steroid Biochemistry and Molecular Biology · 1998 · 42 citations
    2. Apparent Cortisone Reductase Deficiency: A Rare Cause of Hyperandrogenemia and Hypercortisolism Hormone Research in Paediatrics · 2000 · 41 citations
    3. 5α-Reductase activity in the human hair follicle concentrates in the dermal papilla Archives of Dermatological Research · 1998 · 41 citations
    4. Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome The Journal of Clinical Endocrinology & Metabolism · 2016 · 40 citations
    5. Scalp Reduction as an Adjunct to Hair Transplantation: Review of Relevant Literature and Presentation of an Improved Technique The Journal of Dermatologic Surgery and Oncology · 1980 · 40 citations
    6. Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite Therapeutic Drug Monitoring · 2007 · 39 citations
    7. Dutasteride: a review of current data on a novel dual inhibitor of 5alpha reductase. PubMed · 2005 · 38 citations
    8. Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition Psychoneuroendocrinology · 2018 · 37 citations
    9. Inhibition of Rat 5<i>α</i>-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of<i>Quercus acutissima</i>Cortex Evidence-based Complementary and Alternative Medicine · 2015 · 37 citations
    10. The Aromatase Inhibitor Fadrozole and the 5-Reductase Inhibitor Finasteride Affect Gonadal Differentiation and Gene Expression in the Frog <i>Silurana tropicalis</i> Sexual Development · 2009 · 37 citations
    11. MK-386, an Inhibitor of 5α-Reductase Type 1, Reduces Dihydrotestosterone Concentrations in Serum and Sebum without Affecting Dihydrotestosterone Concentrations in Semen<sup>1</sup> The Journal of Clinical Endocrinology & Metabolism · 1997 · 37 citations
    12. Decreased fertility in male rats administered the 5α-reductase inhibitor, finasteride, is due to deficits in copulatory plug formation Reproductive Toxicology · 1991 · 37 citations
    13. Intracrine and Myotrophic Roles of 5α-Reductase and Androgens Medicine and science in sports and exercise · 2011 · 35 citations
    14. Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility1 Biology of Reproduction · 2004 · 35 citations
    15. Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism Fundamental and applied toxicology · 1994 · 35 citations
    16. 7 Regulation of androgen receptor and 5α-reductase in the skin of normal and hirsute women Clinics in endocrinology and metabolism · 1986 · 35 citations
    17. Long-term Oral Administration of 5α-reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats Urology · 2013 · 34 citations
    18. <i>Curcuma aeruginosa</i>, a novel botanically derived 5α-reductase inhibitor in the treatment of male-pattern baldness: a multicenter, randomized, double-blind, placebo-controlled study Journal of Dermatological Treatment · 2011 · 34 citations
    19. Effect of thioredoxin reductase 1 on glucocorticoid receptor activity in human outer root sheath cells Biochemical and Biophysical Research Communications · 2007 · 34 citations
    20. Minoxidil increases 17β-hydroxysteroid dehydrogenase and 5α-reductase activity of cultured human dermal papilla cells from balding scalp Journal of Dermatological Science · 1999 · 34 citations
    21. Safety concerns regarding 5α reductase inhibitors for the treatment of androgenetic alopecia Current Opinion in Endocrinology, Diabetes and Obesity · 2015 · 33 citations
    22. Evaluation of 5α-reductase inhibitory activity of certain herbs useful as antiandrogens Andrologia · 2013 · 33 citations
    23. In Vitro and In Vivo Skin Distribution of 5α-Reductase Inhibitors Loaded Into Liquid Crystalline Nanoparticles Journal of Pharmaceutical Sciences · 2017 · 32 citations
    24. Inhibition of 5α‐Reductase Activity in Late Pregnancy Decreases Gestational Length and Fecundity and Impairs Object Memory and Central Progestogen Milieu of Juvenile Rat Offspring Journal of Neuroendocrinology · 2011 · 32 citations
    25. Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men Advances in Experimental Medicine and Biology · 2017 · 31 citations
    26. The Effect of 5 -Reductase Inhibitors on Erectile Function International Journal of Andrology · 2008 · 31 citations
    27. 5α-Reductase inhibitors in androgenetic alopecia Current Opinion in Endocrinology, Diabetes and Obesity · 2014 · 29 citations
    28. Key targets of hormonal treatment of prostate cancer. Part 2: the androgen receptor and 5α-reductase BJU international · 2009 · 29 citations
    29. Exercise activates the PI3K-AKT signal pathway by decreasing the expression of 5α-reductase type 1 in PCOS rats Scientific reports · 2018 · 28 citations
    30. Long-term use of 5α-reductase inhibitors and the risk of male breast cancer Cancer Causes & Control · 2014 · 28 citations